Cancer Immunotherapy and Biomarkers
Moving in Cancer Cell, Cell, Cellular & molecular immunology and JAMA.
- Moved, week to 22 Oct 2026
- 5
- Papers in 60 days
- 104
Rebuilt
Moved this week
GABA upregulation in TLS-positive tumors is linked to resistance to immune checkpoint inhibitors in ccRCC and STS patients.
- 6 cites
Microbiota-driven stem-like lymphoid niche with CD70+ ILC2s sustains progenitor exhausted T cells, redefining TLS-associated antitumor immunity.
IGF2BP2 promotes bladder cancer lung metastasis by enhancing complement C3 translation and remodeling the immune microenvironment.
Estrogen-driven activation of STING signaling promotes neutrophil extracellular trap formation, causing female-biased resistance to ADC therapy in pancreatic cancer models.
Latest in Cancer Immunotherapy and Biomarkers
Newest first · last 60 days
A therapy-resistant CD44v9+ cancer stem cell population persists in pancreatic ductal adenocarcinoma tissues and organoid models despite treatment with cabozantinib and immunotherapy.
- Open access
- 1 cites
Spatial transcriptomics reveals distinct tumor cell states and multicellular niches along the core-edge axis in glioblastoma.
- Open access
- 4 cites
Adenoma immune profiles, especially CD3+ T cell density, predict future colorectal neoplasia with an odds ratio of 1.44 in a bowel screening cohort.
- Open access
Elevated TFAM expression in dendritic cells is linked to poor response to neoadjuvant immunochemotherapy in residual ESCC.
VEGF-C-driven lymphangiogenesis enables durable complete responses to oncolytic virotherapy in mouse melanoma models.
- Open access
Lymph node-tumor ecosystem remodeling during gastric cancer metastasis involves dynamic immune cell changes and is linked to specific molecular pathways.
- Open access
Personalized neoantigen-targeting cancer vaccines showed safety and immune activity in high-grade epithelial ovarian cancer patients, with 75% of recurrent patients vaccinated.
Activating PPARδ in immune cells enhances tumor suppression and improves immunotherapy responses in mice with metastatic colorectal cancer.
- Open access
High JAK-STAT pathway activity in breast cancer correlates with improved immunotherapy response, especially in triple-negative breast cancer patients, serving as a predictive biomarker.
- Open access
- 1 cites
Cancers evade T cell detection by avoiding presentation of p53 neoantigens through multiple mechanisms, including mutation localization and HLA allele loss.
γδ T cells activated by a BiTE can target small cell lung cancer independently of MHC-I expression, overcoming limitations of CD8+ T cell responses.
High γδ T cell infiltration in small cell lung cancer predicts improved response to anti-PD-L1 immunotherapy.
- Open access
IGF2BP2 promotes bladder cancer lung metastasis by enhancing complement C3 translation and remodeling the immune microenvironment.
ITK deficiency nearly completely prevents autoimmune pulmonary hemorrhage by enhancing regulatory T cell function in a mouse model.
- Open access
Single-cell analysis reveals five distinct tumor microenvironment ecotypes in multiple myeloma, with one linked to tumor expansion and poor clinical outcomes.
CTHRC1-expressing CAFs are linked to poor outcomes and immune resistance in both pMMR/MSS and dMMR/MSI colorectal cancers.
- Open access
- 2 cites
Chinese expert consensus provides graded recommendations on perioperative immune checkpoint inhibitor use and organ-preserving strategies for locally advanced rectal cancer.
- Open access
- 2 cites
Deoxysphingolipids activate cGAS-STING and suppress tumor growth in colon cancer models.
- Open access
Multimodal biomarkers combining liquid biopsy, AI-based imaging, and tumor immune profiling may improve early detection and immunotherapy assessment in hepatocellular carcinoma.
- Open access
TLR9-activated B cells enhance CD8+ T-cell antitumor activity via a CD2-dependent costimulation axis in cancer therapy.
- Open access
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Journals this month
- bioRxiv6244
- medRxiv1789
- PNAS447
- Sci Adv354
- JAMA268
- Environ Res246
- BMJ196
- Nat Commun173
- Environ Pollution167
- Nature151
- Applied & Environ Microbio145
- Science141
- Lancet128
- Cell Rep127
- NEJM119
- Plant Cell Environ118
- J Exp Bot107
- mBio107
Topics moving, week to 22 Oct 2026
- Single-cell and spatial transcriptomics6
- Neuroinflammation and Neurodegeneration Mechanisms5
- Cancer Immunotherapy and Biomarkers5
- Gut microbiota and health5
- Cancer Genomics and Diagnostics4
- Bacteriophages and microbial interactions4
- CAR-T cell therapy research3
- Lung Cancer Treatments and Mutations3
- Liver Disease Diagnosis and Treatment3
- Dementia and Cognitive Impairment Research3