Obinutuzumab significantly improves disease activity in adults with active systemic lupus erythematosus, achieving a 23.1 percentage point higher response rate than placebo at week 52.
- 3 cited this week
New England Journal of Medicine
Massachusetts Medical Society · General Science & Medicine · ISSN 0028-4793, 1533-4406
- Impact (2-yr)
- 32.7
- h-index
- 1.5K
- Open access
- 13%
- Works
- 191.4K
- Papers this month
- 119
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Selpercatinib significantly improves 2-year event-free survival in early-stage RET fusion-positive NSCLC, reaching 92% in stage II/IIIA patients compared to 61% with placebo.
- 14 cites
Talquetamab combined with daratumumab and pomalidomide significantly prolongs progression-free survival in relapsed or refractory multiple myeloma, with 24-month estimates over 81%.
- 14 cites
Latest in NEJM
Newest first · last 60 days
Retatrutide significantly reduces the apnea-hypopnea index by up to 34.3 events per hour in adults with moderate-to-severe obstructive sleep apnea and obesity.
A single intravenous infusion of lonvoguran ziclumeran reduces hereditary angioedema attack rates by 87% compared to placebo in a phase 3 trial.
Long-acting injectable cabotegravir plus rilpivirine is noninferior to oral dolutegravir-based therapy in maintaining viral suppression among African adults with adherence challenges.
Oral icotrokinra at doses of 100 mg, 200 mg, and 400 mg significantly improves clinical response in adults with moderately to severely active ulcerative colitis compared to placebo at week 12.
Approximately 2.5% of adults worldwide have ADHD, which often coexists with psychiatric and somatic conditions, yet remains frequently unrecognized and undiagnosed.
Ponatinib plus blinatumomab significantly improves 24-month event-free survival to 86% in adult Ph-positive ALL compared to 67% with imatinib and chemotherapy.
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Topics moving, week to 22 Oct 2026
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- Neuroinflammation and Neurodegeneration Mechanisms5
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