State predicts cellular perturbation effects across diverse contexts with over 30% improved discrimination on large datasets.
- 6 cited this week
Single-cell and spatial transcriptomics
Moving in Cell, Cancer Cell, Nature Cell Biology and Nature Communications.
- Moved, week to 22 Oct 2026
- 6
- Papers in 60 days
- 265
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Molecular phenotypes and spatial archetypes reveal distinct CAF identities linked to tissue context, advancing precision targeting in cancer therapy.
- 3 cited this week
- Open access
AI model "Path2Space" predicts spatial gene expression from histopathology slides, accurately inferring thousands of genes and outperforming 21 established methods in breast cancer.
- 3 cited this week
- Open access
Dreamlet enables fast, memory-efficient differential expression analysis of large-scale single-cell transcriptomics data, accurately identifying gene-trait associations across 150 Alzheimer's cases.
- 1 on Bluesky
- Open access
RNA fingerprinting accurately assigns single-cell transcriptional responses to perturbations, resolving combinatorial effects and scaling to genome-wide screens.
Spatial multi-omic atlas reveals distinct hepatocyte- and cholangiocyte-lineage programs and cardiac progenitors in a CS12 human embryo.
- Open access
Latest in Single-cell and spatial transcriptomics
Newest first · last 60 days
Spatial multi-omic atlas reveals distinct hepatocyte- and cholangiocyte-lineage programs and cardiac progenitors in a CS12 human embryo.
- Open access
Early lineage divergence in the embryonic mouse thalamus segregates sensory and motor-associative identities from distinct progenitor domains.
- Open access
Multidrug-resistant Klebsiella pneumoniae infection causes immune activation, macrophage heterogeneity, and fibrosis in porcine lungs at single-cell resolution.
- Open access
A non-canonical reactive astrocyte state (Ast10) is linked to neuropathologies and cognitive decline in Alzheimer's disease across diverse human brains.
- Open access
- 14 cites
Monocyte-lineage expansion is linked to transcriptomic individuality in genetically identical Dasypus novemcinctus quadruplets, with the most distinct individual showing increased monocytes.
- Open access
Spatial transcriptomics reveals distinct tumor cell states and multicellular niches along the core-edge axis in glioblastoma.
- Open access
- 4 cites
LUNA, a generative AI model, accurately reconstructs tissue architecture from dissociated gene expression profiles, demonstrated by inferring spatial locations in over 1.2 million cells from the mouse brain atlas.
- Open access
- 6 cites
A chromosome-scale genome and root single-cell atlas reveal genetic divergence and key regulatory genes in Olea europaea subsp. cuspidata, supporting stress tolerance research.
Lymph node-tumor ecosystem remodeling during gastric cancer metastasis involves dynamic immune cell changes and is linked to specific molecular pathways.
- Open access
A modular lentiviral system enables multiplexed gene perturbation revealing hormone receptor interdependence in breast cancer growth in vivo.
- Open access
HERO reduces and refines whole-brain atlas-mapped cellular datasets by enabling hierarchical analysis, improving data clarity and reproducibility across neuroscience studies.
- Open access
Single-cell and spatial genomics reveal complex gene regulation in trophoblasts at the human maternal-fetal interface.
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Journals this month
- bioRxiv6244
- medRxiv1789
- PNAS447
- Sci Adv354
- JAMA268
- Environ Res246
- BMJ196
- Nat Commun173
- Environ Pollution167
- Nature151
- Applied & Environ Microbio145
- Science141
- Lancet128
- Cell Rep127
- NEJM119
- Plant Cell Environ118
- J Exp Bot107
- mBio107
Topics moving, week to 22 Oct 2026
- Single-cell and spatial transcriptomics6
- Neuroinflammation and Neurodegeneration Mechanisms5
- Cancer Immunotherapy and Biomarkers5
- Gut microbiota and health5
- Cancer Genomics and Diagnostics4
- Bacteriophages and microbial interactions4
- CAR-T cell therapy research3
- Lung Cancer Treatments and Mutations3
- Liver Disease Diagnosis and Treatment3
- Dementia and Cognitive Impairment Research3