bioRxiv

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Papers this month: 6244

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Early Insulin Signaling Defects and Oxidative Stress Kinase Activation Precede Tau Pathology in PS19 Tau Transgenic Mice
bioRxiv · 22 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.10.16.759692
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Opposing plasticity mechanisms enhance visual inputs that violate their context
bioRxiv · 22 Oct 2026 · Preprint
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https://jclub.com.au/a/10.1101/2024.06.10.598181
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Reduced baseline male fertility and increased sensitivity to hypoxic stress in high-elevation deer mice
bioRxiv · 22 Oct 2026 · Preprint
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Shared landscapes, shared risk: Echinococcus multilocularis infection in coyotes is linked to agricultural land and altered green space in a major U.S. metropolitan area
bioRxiv · 22 Oct 2026 · Preprint
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Signature Recontextualization: Mapping perturbational signatures across biological contexts
bioRxiv · 22 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.08.14.744937
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A dedicated motif in human polymerase gamma enables DNA synthesis through replication roadblocks
bioRxiv · 22 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.27.754746
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Acute scalp EEG signatures of anterior thalamic DBS in epilepsy:reproducible gamma power enhancement within an aperiodic spectral-state shift
bioRxiv · 22 Oct 2026 · Preprint
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SpacePath enables pathway and molecular-family analysis beyond annotation ambiguity in spatial metabolomics and lipidomics
bioRxiv · 22 Oct 2026 · Preprint
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Pose: a pure-NumPy, chirality-aware, structural engine for building and manipulating the molecular structures of proteins, nucleic acids, and small organic molecules
bioRxiv · 22 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.10.19.760100
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How AlphaFold 3 helps with multiscale drug discovery
bioRxiv · 22 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.10.19.757941
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A pilot computer-vision model trained to identify slide-mounted scale insect pests from the family Rhizoecidae
bioRxiv · 22 Oct 2026 · Preprint
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CCTP-Atlas: Compartment-Resolved Ciliary Transcriptional Dysregulation in Tetralogy of Fallot, A Six-Dataset Integrative Meta-Analysis
bioRxiv · 22 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.10.12.758603
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Emergence of long- and short-range functional connectivity parallels the development of neonatal brain gradients
bioRxiv · 22 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.05.19.726280
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The AP-1 clathrin adaptor has a conserved role in recycling resident proteins of the trans-Golgi network
bioRxiv · 22 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.10.21.760840
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Multiple bottlenecks constrain presentation of Mycobacterium tuberculosis antigens on MHC class I
bioRxiv · 22 Oct 2026 · Preprint
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Small molecules targeting BRCA1-deficient cancer cells
bioRxiv · 22 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.10.21.760761
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Instrumental-Motor Transfer: The Relative Value of Competing Movement Goals Modulates Implicit Motor Learning
bioRxiv · 22 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.06.22.733849
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Coiled-coil homo-oligomerization and disaggregase Hsp104 act in parallel to stabilize orphan septins
bioRxiv · 22 Oct 2026 · Preprint
Orphan yeast septins are stabilized by coiled-coil homodimers, trimers, and the disaggregase Hsp104, preventing aggregation and proteasomal degradation.
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https://jclub.com.au/a/10.64898/2026.03.09.710472
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Systematic mapping of the prokaryotic noncoding sequence space with a genomic language model
bioRxiv · 22 Oct 2026 · Preprint
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Calcium-Driven Activation of Gelsolin: Mechanism and the Active-State Ensemble
bioRxiv · 22 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.10.16.759396
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Multi-timescale dynamics organize descending pain modulation
bioRxiv · 22 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2025.12.15.693905
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Differential Gene Expression in the Tropical House Cricket and Its Iridovirus in Healthy versus Diseased Specimens
bioRxiv · 22 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.05.19.726264
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Development of CYP8B1-specific inhibitors for metabolic diseases
bioRxiv · 22 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.10.20.760253
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When does heterogeneity average out in coarse-grained ecological communities?
bioRxiv · 22 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.10.09.757735
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N-Acetylglucosamine ameliorates knee osteoarthritis by enhancing UDP-GlcNAc conversion and chondrocyte DNA repair capacity
bioRxiv · 22 Oct 2026 · Preprint
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Structured recurrence of latent neural processes predicts memory recognition performance
bioRxiv · 22 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.10.16.759557
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Morphofunctional Characterization of Colonic Organoids from Muc2-/- Mice
bioRxiv · 22 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.10.21.760621
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Statistical analysis provides new insights into patterns and mechanisms of the WANCY hotspot on vertebrate mitochondrial genomes
bioRxiv · 22 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.10.16.759661
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Activation of basal forebrain cholinergic neurons promotes the attribution of incentive salience to reward cues in male rats
bioRxiv · 22 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.10.20.760494
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Toward naturalistic reaching: Intermediate reaches under uncertainty generalize to walking, but are not obligatory
bioRxiv · 22 Oct 2026 · Preprint
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