Elevated blood-based p-tau217 levels predict up to 38% risk of cognitive impairment over 10 years in unimpaired older adults.
- 6 cites
Dementia and Cognitive Impairment Research
- Moved, week to 22 Oct 2026
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- Papers in 60 days
- 46
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A single Centiloid cutoff of 18 best distinguishes amyloid positivity in PET scans across diverse studies, with a high predictive value for visual reads.
- 7 cites
Blood biomarkers and digital measures together can improve Alzheimer’s disease care beyond diagnostic accuracy alone.
Latest in Dementia and Cognitive Impairment Research
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Mendelian randomization and multiomics analyses identified 19 druggable targets for Alzheimer's disease, including protective variants in EPHX2, in individuals of European and African ancestry.
- Open access
Hepatic expression of APOE3 Christchurch reduces amyloid-β burden and AD pathologies in APOE4-expressing APP/PS1 mice.
- 1 cites
A single Centiloid cutoff of 18 best distinguishes amyloid positivity in PET scans across diverse studies, with a high predictive value for visual reads.
- 7 cites
APOE-stratified GWAS identified new genetic signals for Alzheimer's disease risk, including DDHD1, with effects specific to APOE ε4 and ε2 carrier status.
- Open access
Functional connectivity changes linked to aging and Alzheimer's disease are aligned with distinct hierarchical brain communication axes, with AD associated with the sensory-association axis and aging with the representation-executive axis.
- Open access
DeepFS achieves 89.45% accuracy and 0.9647 AUC in diagnosing Alzheimer's disease from brain tissue transcriptomic data.
- Open access
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Journals this month
- bioRxiv6244
- medRxiv1789
- PNAS447
- Sci Adv354
- JAMA268
- Environ Res246
- BMJ196
- Nat Commun173
- Environ Pollution167
- Nature151
- Applied & Environ Microbio145
- Science141
- Lancet128
- Cell Rep127
- NEJM119
- Plant Cell Environ118
- J Exp Bot107
- mBio107
Topics moving, week to 22 Oct 2026
- Single-cell and spatial transcriptomics6
- Neuroinflammation and Neurodegeneration Mechanisms5
- Cancer Immunotherapy and Biomarkers5
- Gut microbiota and health5
- Cancer Genomics and Diagnostics4
- Bacteriophages and microbial interactions4
- CAR-T cell therapy research3
- Lung Cancer Treatments and Mutations3
- Liver Disease Diagnosis and Treatment3
- Dementia and Cognitive Impairment Research3