mBio
American Society for Microbiology · Microbiology & Mycology · ISSN 2150-7511
- Impact (2-yr)
- 6.3
- h-index
- 228
- Open access
- 100%
- Works
- 9.2K
- Papers this month
- 107
Rebuilt
Moved this week
CysK2-mediated cysteine biosynthesis is essential for copper resistance in Mycobacterium tuberculosis, with a single amino acid substitution in H37Rv impairing this function.
- 1 cites
Pathway remodeling and adaptive evolution enabled Escherichia coli to co-utilize glucose and xylose efficiently, achieving improved bioconversion of lignocellulosic biomass.
- Open access
- 1 cites
Human transferrin receptor 1 (hTfR) acts as a critical entry co-receptor for parvovirus B19, facilitating viral internalization into human erythroid progenitor cells.
- 2 cites
Streptococcus anginosus promotes gastric cancer through its metabolites, exerting stronger pro-tumorigenic effects than Helicobacter pylori's contact-dependent mechanisms.
- 1 cites
The canine gut microbiome shares significant taxonomic and functional similarities with humans, making dogs a valuable model for microbiome research related to health and aging.
- 1 cites
Latest in mBio
Newest first · last 60 days
Competitive interactions in six-species synthetic denitrifying communities significantly enhance denitrification rates during experimental evolution.
- Open access
Transient mitochondrial heteroplasmy in Zymoseptoria tritici enables rapid switching between fungicide resistance genotypes, with alleles G143A and Y132C coexisting within individual cells.
- Open access
Cross-linking mass spectrometry enhances structure prediction of disordered Encephalitozoon hellem proteins with no clear homologs.
Pathogenic Leptospira increases glucose uptake and metabolism specifically at host-like 37°C, challenging previous assumptions of limited glucose utilization.
Persistent HIV-1 transcription in myeloid cells during ART is linked to chronic immune activation and inflammation in people with HIV.
A novel Totivirus infecting Cryptococcus neoformans was identified in six clinical isolates from HIV-positive patients with cryptococcal meningitis.
Hikarchaeia, a group of uncultivated Archaea, exhibit distinct seasonal and vertical distribution patterns, with relative abundance peaking at ~1% of prokaryotic amplicons in the North Atlantic Gyre.
Obesity-associated acetate depletion impairs antibiotic efficacy against Acinetobacter baumannii by reducing immune activation and increasing bacterial tolerance.
Dirammox genes are present in 690 genomes across 3 phyla and 26 genera, with nearly ubiquitous occurrence in Alcaligenes, Delftia, and Microvirgula.
Craig Venter pioneered the first bacterial genome sequencing and revealed the vast diversity of microbial life, transforming microbiology and vaccinology.
Psc1, an RNA-binding protein in Cryptococcus neoformans, suppresses CO2 tolerance by sequestering key mRNAs when unphosphorylated, impairing growth under high CO2 conditions.
Two decades of in vivo coral microbiome manipulations have identified common taxa and research gaps to improve coral health.
Yersinopine is a primary zinc acquisition system in Yersinia pseudotuberculosis, essential for growth under zinc-limited conditions, unlike in Yersinia pestis where it is inactive.
- Open access
A histidine substitution at position 413 in the S1 subunit of IBV enhances viral attachment to DF-1 cells by promoting binding to α-2,3-linked sialic acids on gangliosides.
CRISPR transposition and overexpression (CRISPRtOE) enables targeted, genome-scale gene upregulation in Proteobacteria, including Escherichia coli and Zymomonas mobilis.
Methanotrophs dissipate up to 60% of substrate energy as heat, with heat yields surpassing other aerobic microbes, indicating their potential for methane mitigation and energy recovery.
Genomic diversity in marine Synechococcus explains most variation in nutrient stress plasticity, with non-core protein expression predicting deviations in elemental regulation.
A hybrid protein vaccine containing mapped MHC-II/CD4+ T-cell epitopes from C. neoformans protects DR4 mice from lethal pulmonary cryptococcosis.
TIAR protein facilitates rapid initiation of West Nile virus genome RNA synthesis by binding cooperatively to the 3'(-) stem-loop RNA in infected cells.
CysK2 links copper sensing to redox homeostasis, enabling Mycobacterium tuberculosis to persist during infection, with cysK2-deficient mutants showing reduced long-term survival in mice.
Benchmarking microbial behavior in natural environments is essential to validate and improve experimental infection models.
Monoclonal antibodies against JUNV GPC show broad reactivity and protect in vivo, with five reducing viral loads in a mouse challenge model.
Flagella are essential for activating aggregation factors necessary for T6SS-mediated competition in high-viscosity environments in Vibrio fischeri MJ11.
HCMV US30 promotes viral multiplication by inducing mitochondrial fission and apoptosis through TMED10 and DRP1 interactions.
Pre-existing systemic and nasal antibodies against avian H5 influenza A viruses vary by birth year and childhood imprinting, with those born before 1957 showing higher levels.
Experimental models and clinical studies reveal distinct relapse mechanisms in tuberculosis, with clinical relapse driven by non-replicating bacteria and experimental relapse by residual replicating bacteria.
A non-replicating adenoviral vector delivering recombinant HMGB1 Box A reduces inflammation in multiple HMGB1-driven disease models.
CT226 effector protein of Chlamydia trachomatis recruits a host multiprotein complex via direct binding, modulating inclusion size and bacterial progeny production.
- Open access
MAIT cells exhibit tissue-dependent responses to S. aureus and show variable sensitivity to HlgAB toxin, with tonsillar MAIT cells being notably resistant.
- Open access
Starved Pseudomonas synxantha cells enhance desiccation tolerance by rigidifying membranes, despite not synthesizing osmolyte NAGGN during water and nutrient limitations.
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Journals this month
- bioRxiv6244
- medRxiv1789
- PNAS447
- Sci Adv354
- JAMA268
- Environ Res246
- BMJ196
- Nat Commun173
- Environ Pollution167
- Nature151
- Applied & Environ Microbio145
- Science141
- Lancet128
- Cell Rep127
- NEJM119
- Plant Cell Environ118
- J Exp Bot107
- mBio107
Topics moving, week to 22 Oct 2026
- Single-cell and spatial transcriptomics6
- Neuroinflammation and Neurodegeneration Mechanisms5
- Cancer Immunotherapy and Biomarkers5
- Gut microbiota and health5
- Cancer Genomics and Diagnostics4
- Bacteriophages and microbial interactions4
- CAR-T cell therapy research3
- Lung Cancer Treatments and Mutations3
- Liver Disease Diagnosis and Treatment3
- Dementia and Cognitive Impairment Research3