Nature Cancer
Nature Portfolio · Oncology · ISSN 2662-1347
- Impact (2-yr)
- 18.1
- h-index
- 132
- Open access
- 51%
- Works
- 1.2K
- Papers this month
- 10
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Latest in Nat Cancer
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Reversible cellular plasticity enables tumor cells to bypass targeted therapies, contributing to drug tolerance and resistance in cancer treatment.
Intestinal epithelial GSK3β regulates fumarate-dependent neutrophil reprogramming that promotes colorectal cancer progression.
Stroke promotes glioma progression by inducing tumor-associated astrocytes with reduced Ca(2+) activity and increasing tumor-associated microglia and macrophages.
Complex mutational phenomena in human cancers are characterized by distinct genomic patterns, with phenomena like chromothripsis and chromoplexy linked to specific molecular mechanisms.
An iron-dependent methionine redox pathway is essential for adipose browning and influences cachexia progression in mouse models.
- Open access
- 1 cites
CROWN achieves over 95% accuracy in 48 cytology patch-level classifications, establishing it as a highly effective universal model for computational cytopathology.
Circulating tumor DNA-guided treatment in high-risk stage II and III colon cancer achieved a 2-year relapse-free rate of 88% among ctDNA-negative patients, but did not meet the predefined threshold.
- Open access
MMSDH-mediated ACSL4 propionylation at K606 is linked to ferroptosis evasion and poor chemotherapy response in PDAC.
Commensal Nakaseomyces glabratus translocates from the gut to prostate tumors, accelerating cancer progression and worsening patient survival in castration-resistant prostate cancer.
- Open access
F-actin-FcγR bridging enhances tumor control and synergizes with therapy in mouse cancer models.
- Open access
Adding L-glutamine to gemcitabine and nab-paclitaxel nearly doubled the overall survival to 22 months in advanced pancreatic ductal adenocarcinoma patients.
- Open access
In vivo CAR T cell engineering can directly generate therapeutic T cells within patients, potentially overcoming manufacturing barriers and expanding access to cancer treatment.
Lactate-α-ketoglutarate metabolic circuit in tumor-infiltrating Treg cells promotes tumor progression by inducing NK cell senescence, with GDH1 as a key driver.
Fc-optimized human anti-GITR antibody enhances antitumor efficacy by promoting CD4 T cell-dendritic cell crosstalk in humanized mice.
- Open access
SlideChat achieves a 19.1% higher accuracy in interpreting gigapixel-scale whole-slide images across 31 cancer types, outperforming existing models in computational pathology.
Targeting PID1 in tumor-associated macrophages produces oxysterols that reprogram macrophages toward an antitumor phenotype, enhancing immune responses in multiple cancers.
Galanin promotes immunosuppression and ferroptosis resistance in glioblastoma by enhancing myeloid-derived suppressor cell infiltration, leading to immunotherapy resistance in mouse models.
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Topics moving, week to 22 Oct 2026
- Single-cell and spatial transcriptomics6
- Neuroinflammation and Neurodegeneration Mechanisms5
- Cancer Immunotherapy and Biomarkers5
- Gut microbiota and health5
- Cancer Genomics and Diagnostics4
- Bacteriophages and microbial interactions4
- CAR-T cell therapy research3
- Lung Cancer Treatments and Mutations3
- Liver Disease Diagnosis and Treatment3
- Dementia and Cognitive Impairment Research3