A novel Acinetobacter baumannii phage causes capsule loss, reducing bacterial virulence and increasing biofilm formation in resistant strains.
- 1 cites
Bacteriophages and microbial interactions
Moving in Cell Host & Microbe, Journal of bacteriology, mSystems and Virulence.
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Modular architecture of phage defense systems enables the discovery of three new systems in Pseudomonas aeruginosa.
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Nucleocytoviricota are identified as central, highly influential entities shaping microbial community structure in wastewater treatment plants, with 61 genomes recovered from 23 sites.
- Open access
Approximately 56% of SAR11 ortholog groups are classified as unknome, with 57 conserved orthologs inferred to be involved in substrate uptake, nucleotide utilization, and viral defense.
- Open access
Small HK97-fold viral genomes linked to procapsids suggest bidirectional evolution between viruses and encapsulins.
- Open access
MDL-001 is the first broad-spectrum oral antiviral demonstrating in vivo efficacy against multiple RNA viruses, including influenza, RSV, SARS-CoV-2, and hepatitis B/C, with nanomolar potency.
- Open access
- 4 cites
The bacteriophage transcription factor Gp53 suppresses Pseudomonas aeruginosa growth, motility, and biofilm formation by regulating key host genes.
- Open access
Cyanophage-encoded thioredoxin and virulence enhancer genes significantly boost phage fitness and infection success in marine Synechococcus, with thioredoxin increasing replication and cve enhancing virulence.
- Open access
- 2 cites
Infection cycles of Nucleocytoviricota viruses share core features such as membrane fusion entry, viral factory formation, genome replication, and virion morphogenesis, despite lineage-specific differences.
Coliphage HY126 encodes a novel two-step arabinofuranosylation system that modifies cytosine with diarabinofuranosyl-5-hydroxycytosine in DNA.
- 2 cites
Re-examining the temperate phage life cycle reveals unanticipated complexities and emphasizes the importance of viewing properties of (pro)phages as integral to their overall cycle.
Structural insights reveal that transcription regulators and nucleoid-associated proteins remodel DNA conformation to influence prokaryotic adaptation and host-invader interactions.
- Open access
Phage-encoded host-acting transcription and sigma factors (TSFs) are prevalent in phages and may significantly influence host cellular functions beyond traditional AMGs.
3D DNA walker-based biosensors can detect foodborne pathogens with high sensitivity through programmable motion control and signal amplification.
- 2 cites
A machine-learning framework predicts strain-level phage-host interactions across diverse bacteria with AUROC up to 0.94, independent of phylogenetic constraints.
- Open access
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- Nature151
- Applied & Environ Microbio145
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- Lancet128
- Cell Rep127
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Topics moving, week to 22 Oct 2026
- Single-cell and spatial transcriptomics6
- Neuroinflammation and Neurodegeneration Mechanisms5
- Cancer Immunotherapy and Biomarkers5
- Gut microbiota and health5
- Cancer Genomics and Diagnostics4
- Bacteriophages and microbial interactions4
- CAR-T cell therapy research3
- Lung Cancer Treatments and Mutations3
- Liver Disease Diagnosis and Treatment3
- Dementia and Cognitive Impairment Research3