Nature
Nature Portfolio · General Science & Medicine · ISSN 0028-0836
- Impact (2-yr)
- 19.5
- h-index
- 1.8K
- Open access
- 17%
- Works
- 449.1K
- Papers this month
- 151
Rebuilt
Moved this week
A biobank of 256 patient-derived tumour organoids reveals diverse gene dependencies across multiple cancer types, advancing precision oncology.
- 3 cited this week
- Open access
A large-scale international effort created 665 next-generation patient-derived cancer models with 97.8% genetic and 95% epigenetic fidelity to original tumors, covering 25 cancer types.
- 2 cited this week
- Open access
Latest in Nature
Newest first · last 60 days
Wireless mesoscope Airscope achieves 4 μm resolution over a 6 mm field of view at 12.5 Hz in freely moving mice, enabling large-scale cortical imaging.
Nearly half (44%) of assessed reef-building coral species are classified as threatened on the IUCN Red List due to climate change-related risks.
A 22-month public-health intervention in Honduran villages rewired social networks by increasing ties among treated individuals and decreasing ties between treated and untreated individuals, lasting for three years.
Wave coarsening in active elastic media leads to the formation of a time crystal, with vibrations growing in wavelength, period, and amplitude before global synchronization.
Early tetrapod necks were surprisingly rigid, with most stem tetrapods able to move their heads less than 6° laterally and less than 3° dorsally, and unable to rotate.
Chemically induced totipotent-like stem cells can autonomously recapitulate the entire early mouse embryogenesis, including development up to E10.5 with functional tissues.
De novo designed metalloproteases achieve up to 10^10-fold acceleration of peptide bond hydrolysis and selectively cleave disease-related proteins with rate enhancements up to 10^9-fold.
Rh(3+) stabilized in KRh@MFI catalyzes hydroformylation with a record linear to branched aldehyde ratio of 817 at 96% undecanal selectivity.
Artificial intelligence-enabled analysis reveals that higher brown adipose tissue activity is linked to lower prevalence of cardiometabolic and psychiatric diseases in humans.
Elp1 is essential for the generation of myeloid cells during brain microglia repopulation in a genetic screen of 20,000 perturbations.
Probabilistic bias correction doubles the subseasonal skill of AI weather forecasts and improves dynamical model accuracy for 91% of pressure, 92% of temperature, and 98% of precipitation targets.
Capillary-selective vasodilation via myosin inhibition with R(+)2501 rapidly restores blood flow and improves survival in reperfused models of myocardial infarction and kidney injury.
Global conservation area coverage likely already exceeds 26.81%, approaching the 30% target set for 2030, based on a representative sample of 25 countries.
Monsoon variability over the past 450,000 years is linked to Milankovitch forcing and internal boundary conditions, with notable out-of-phase behavior between hemispheres.
Genomic evolution in IDH-mutant gliomas diverges between astrocytomas and oligodendrogliomas, with distinct genetic alterations linked to tumor progression and treatment response.
Group IV-V bcc refractory alloys at 20 K show a plateau in tensile yield strength and fracture toughness, with no ductile-to-brittle transition observed.
De novo designed cysteine proteases achieve up to 3 × 10^7 rate enhancement with 19% success rate in hydrolyzing peptide bonds in mammalian cells.
Rhodium-catalyzed spiro-carbon-atom insertion converts biphenylene into complex spirocyclic structures by activating C-C σ-bonds with a single carbon atom.
Cryo-EM structures of the IR8a-IR75k complex from Anopheles stephensi reveal ligand-induced gating mechanisms with four distinct states, including apo and ligand-bound forms.
A tetravalent nanobody-based IL-10 receptor agonist achieves myeloid cell selectivity by relying on TYK2 dependence, avoiding T cell activation in inflammatory models.
Hundreds of new microexons, many with neuron-specific patterns, are identified, and their splicing is predicted to be altered by autism-linked genetic variants.
Targeted stimulation of about 20 M1 L2/3 neurons can induce learned movements and reproduce activity patterns associated with skilled motor behavior in mice.
Sexual dimorphism in epidermal stem cell dynamics shows female mice have synchronized cell division and differentiation, accelerating wound healing.
Helical-edge-mode tunnelling enables atomic-scale spin sensing of two-dimensional d-wave altermagnetism in KV2Se2O.
Catalytic functionalization of polyethylene at a solid-liquid interface enhances surface adhesion up to 90-fold without altering bulk properties, using only 0.001 mol% iron catalyst below 80°C.
A new bacterial antiviral defense system, DRT10, employs a telomerase-like reverse transcription mechanism to produce tandem DNA repeats using ncRNA templates.
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Journals this month
- bioRxiv6244
- medRxiv1789
- PNAS447
- Sci Adv354
- JAMA268
- Environ Res246
- BMJ196
- Nat Commun173
- Environ Pollution167
- Nature151
- Applied & Environ Microbio145
- Science141
- Lancet128
- Cell Rep127
- NEJM119
- Plant Cell Environ118
- J Exp Bot107
- mBio107
Topics moving, week to 22 Oct 2026
- Single-cell and spatial transcriptomics6
- Neuroinflammation and Neurodegeneration Mechanisms5
- Cancer Immunotherapy and Biomarkers5
- Gut microbiota and health5
- Cancer Genomics and Diagnostics4
- Bacteriophages and microbial interactions4
- CAR-T cell therapy research3
- Lung Cancer Treatments and Mutations3
- Liver Disease Diagnosis and Treatment3
- Dementia and Cognitive Impairment Research3