Cancer Cells and Metastasis
Moving in bioRxiv, Cancer Research, Nature Cancer, Gastroenterology, Nature, Nature Communications, Gut and Nature Reviews Cancer.
- Moved, week to 23 Oct 2026
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Latest in Cancer Cells and Metastasis
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A therapy-resistant CD44v9+ cancer stem cell population persists in pancreatic ductal adenocarcinoma tissues and organoid models despite treatment with cabozantinib and immunotherapy.
- Open access
- 1 cites
Combining LGR5- and MET-targeting ADCs with different payloads significantly delays tumor relapse and prolongs survival in preclinical colorectal cancer models.
- Open access
Reactive astrocyte-like tumor cells with mesenchymal and injury-response signatures are enriched after radiotherapy and persist in recurrent glioblastoma in a mouse model.
- Open access
Reversible cellular plasticity enables tumor cells to bypass targeted therapies, contributing to drug tolerance and resistance in cancer treatment.
IGF2BP2 promotes bladder cancer lung metastasis by enhancing complement C3 translation and remodeling the immune microenvironment.
Carmn is a conserved regulator of epithelial basal-cell stemness and Wnt/β-catenin signaling in exocrine glands, essential for tumor formation in mammary tissue.
- Open access
Multi-omics and computational frameworks have significantly advanced understanding of epithelial-mesenchymal transition (EMT) by enabling comprehensive profiling of cellular states at unprecedented resolution.
MYC-driven tumor metabolism varies with tissue type, microenvironment, and systemic factors, revealing context-dependent vulnerabilities that may inform targeted therapies.
Blood-based biomarkers show promise for liver cancer but require further validation before widespread clinical use.
A new iPSC line from a 70-year-old patient with double primary lung and colon cancers maintains normal karyotype and differentiation capacity.
- Open access
Molecular, cellular, and functional organization of nutrient absorption varies regionally along the small intestine, with a comprehensive framework now emerging to define this zonation.
Lineage transformation to squamous identity confers KRAS inhibitor resistance in mouse lung adenocarcinoma models.
Distinct epithelial and fibroblast features are identified in pancreatitis and pancreatic ductal adenocarcinoma (PDAC) using multi-stromal organoid co-cultures.
- Open access
Human-derived cortical organoids transplanted into mouse brains form extensive, integrated xenocortical circuits with diverse human cell types, including layer 5 projection neurons.
- Open access
- 1 cites
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Topics moving, week to 23 Oct 2026
- Single-cell and spatial transcriptomics6
- Neuroinflammation and Neurodegeneration Mechanisms5
- Bacteriophages and microbial interactions5
- Gut microbiota and health5
- Genomics and Phylogenetic Studies4
- Cancer Genomics and Diagnostics4
- Cancer Immunotherapy and Biomarkers4
- Alzheimer's disease research and treatments3
- Inflammatory Bowel Disease3
- Influenza Virus Research Studies3