Monoclonal and Polyclonal Antibodies Research
Moving in bioRxiv, Nature, Nature Biotechnology, Nature Communications, Nature Medicine, Biotechnology advances, Gastroenterology and Nature Cancer.
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Latest in Monoclonal and Polyclonal Antibodies Research
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D2C7-ATC therapy is linked to prolonged survival in a subset of patients with IDHwt recurrent glioblastoma, with a median overall survival of 17.38 months in certain cases.
Antibody–lectin chimeras (AbLecs) outperform conventional antibody therapies in enhancing antitumor immune responses in cancer models.
- Open access
Re-examining the temperate phage life cycle reveals unanticipated complexities and emphasizes the importance of viewing properties of (pro)phages as integral to their overall cycle.
CAR-T cell therapy and cancer nanovaccines are emerging as powerful, potentially complementary immunotherapy strategies with distinct strengths and limitations across studies.
- Open access
CAR T cells targeting surface U5 snRNP200, an RNA helicase absent from normal hematopoietic precursors, show efficacy against AML and B-cell ALL in models.
- Open access
Metastasis-associated migrasomes are enriched in tumor antigens and promote CD8+ T cell responses that constrain metastatic progression.
- Open access
Venetoclax-controlled DROP-CAR T cells enable dose-dependent regulation of tumor targeting, reducing T cell binding to tumor cells in vitro and in vivo.
- Open access
- 2 cites
MARCH2 and MARCH3 redundantly target FcγRI for K27-linked polyubiquitination and lysosomal degradation, limiting inflammatory responses in mice.
Bispecific antibody chimeras (GTACs) induce receptor degradation, achieving over 100-fold greater potency than traditional antagonists for multiple GPCRs.
- Open access
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Topics moving, week to 23 Oct 2026
- Single-cell and spatial transcriptomics6
- Neuroinflammation and Neurodegeneration Mechanisms5
- Bacteriophages and microbial interactions5
- Gut microbiota and health5
- Genomics and Phylogenetic Studies4
- Cancer Genomics and Diagnostics4
- Cancer Immunotherapy and Biomarkers4
- Alzheimer's disease research and treatments3
- Inflammatory Bowel Disease3
- Influenza Virus Research Studies3