Glycosylation and Glycoproteins Research
Moving in bioRxiv, Nature Biotechnology, Nature Chemical Biology, Cell Reports, Blood, Cancer Research, Circulation and Communications Biology.
- Moved, week to 23 Oct 2026
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Latest in Glycosylation and Glycoproteins Research
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Antibody-lectin chimeras (AbLecs) outperform most existing therapies by reducing tumor burden in a humanized mouse model, demonstrating potent glyco-immune checkpoint blockade.
- Open access
- 32 cites
GlycoRNAs, a novel class of small noncoding RNAs covalently modified with N-glycans, reside on the cell surface and reshape RNA regulatory understanding.
- Open access
Antibody–lectin chimeras (AbLecs) outperform conventional antibody therapies in enhancing antitumor immune responses in cancer models.
- Open access
Host N-glycosylation is essential for E. coli infection, facilitating adhesion and secretion system activity through two distinct pathways.
- Open access
Galectin-1 drives monocyte hyperinflammation in myeloproliferative neoplasms, with Lgals1 ablation reducing disease features in mice.
- Open access
Pathogenic O-GlcNAc dyshomeostasis linked to neurodevelopmental defects and behavioral abnormalities in a rodent model of OGT-ID.
- Open access
- 1 cites
Plant-derived pectin forms distinct nanoscale morphologies and demonstrates tight association with animal tissue in a surgical setting.
- Open access
A novel Fab-dimerized glycan (FDG) antibody with a dual-glycan clamp epitope was isolated, showing approximately 30% breadth against HIV-1 and unique architecture.
- Open access
NDST2-driven N-glycosylation of EGFR at four conserved sites promotes lenvatinib resistance in hepatocellular carcinoma, with NDST2 upregulation correlating with resistance.
Folding-mediated secretion using ProAla mutations yields highly pure bispecific antibodies with 100% correct pairing in IgG-like formats.
- Open access
- 1 cites
Large-scale glycomics datasets are revolutionizing understanding of glycan functions, with recent advances enabling extensive studies to uncover biological roles.
Galectin-3 enhances CaV1.2 channel activity and blood pressure, with blocking peptides reducing hypertension by over 35% in rat models.
GlycoRNA biogenesis is significantly impaired in human MASLD livers, with most glycoRNAs reduced by approximately 50%, contributing to disease progression.
- 1 cites
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Topics moving, week to 23 Oct 2026
- Single-cell and spatial transcriptomics6
- Neuroinflammation and Neurodegeneration Mechanisms5
- Bacteriophages and microbial interactions5
- Gut microbiota and health5
- Genomics and Phylogenetic Studies4
- Cancer Genomics and Diagnostics4
- Cancer Immunotherapy and Biomarkers4
- Alzheimer's disease research and treatments3
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