vaccines and immunoinformatics approaches
Moving in bioRxiv, eLife, Applied and environmental microbiology, Biotechnology advances, Cancer Cell, Cell Reports, Frontiers in Genetics and Genome Biology.
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Latest in vaccines and immunoinformatics approaches
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Cancers evade T cell detection by avoiding presentation of p53 neoantigens through multiple mechanisms, including mutation localization and HLA allele loss.
High γδ T cell infiltration in small cell lung cancer predicts improved response to anti-PD-L1 immunotherapy.
- Open access
Deep-learning co-folding methods accurately predicted over 50% of Mac1 ligand poses within 2 Å RMSD for 489 SARS-CoV-2 complexes, despite limited structural rearrangement recapitulation.
- Open access
SCARSE, an AI framework combining ESM2 embeddings with Gaussian process regression, outperforms baselines in low-data peptide engineering tasks with up to 500 samples.
- Open access
Plasmodium sporozoite cell traversal triggers innate immune responses that are essential for protective T cell activation, with traversal-deficient SPZs failing to prime immunity in mice.
- 1 cites
Genetic variation in HLA, IGKV, and HHEX loci significantly influences COVID-19 vaccine-induced neutralizing antibody responses and protection, with HLA linked to reduced breakthrough infections.
- Open access
MS Andrea directly identifies and scores combinatorial peptide modifications, detecting up to four modifications per peptide with higher accuracy than existing tools.
- Open access
AlphaFold2-based PAbFold pipeline accurately predicts linear antibody epitopes from sequence data, successfully identifying epitopes for known and novel antibodies.
- Open access
The Virtual Biotech, a multi-agent AI system, improves drug development success rates by 48% and reduces adverse events by 32% through integrated analysis of biological data.
- 1 cites
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Journals this month
- bioRxiv6131
- medRxiv1703
- PNAS447
- Sci Adv354
- JAMA262
- Environ Res230
- BMJ182
- Environ Pollution165
- Nat Commun161
- Science141
- Nature138
- Lancet128
- Cell Rep120
- NEJM119
- mBio107
- Plant Cell Environ107
- Curr Biol106
- J Exp Bot106
Topics moving, week to 23 Oct 2026
- Single-cell and spatial transcriptomics6
- Neuroinflammation and Neurodegeneration Mechanisms5
- Bacteriophages and microbial interactions5
- Gut microbiota and health5
- Genomics and Phylogenetic Studies4
- Cancer Genomics and Diagnostics4
- Cancer Immunotherapy and Biomarkers4
- Alzheimer's disease research and treatments3
- Inflammatory Bowel Disease3
- Influenza Virus Research Studies3