Disruption of AaSwi6 and AaMbp1 reduces toxin production by over 80% and impairs virulence in A. alternata, highlighting their key role in pathogenicity.
- 1 cited this week
- Open access
Virulence
Taylor & Francis · Microbiology & Mycology · ISSN 2150-5594, 2150-5608
- Impact (2-yr)
- 5.5
- h-index
- 126
- Open access
- 100%
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- 2.6K
- Papers this month
- 12
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Biofilms enable bacteria to resist antibiotics through complex molecular networks, with over 70% of persistent infections linked to biofilm formation.
- Open access
- 4 cites
A novel Acinetobacter baumannii phage causes capsule loss, reducing bacterial virulence and increasing biofilm formation in resistant strains.
- 1 cites
Candida auris exhibits multidrug resistance and causes invasive infections with high mortality rates of 30-60% in humans.
- 4 cites
Penicillium overgrowth and microbial imbalance are linked to fruiting body abortion in artificially cultivated Chinese cordyceps, with Penicillium enrichment correlating with developmental failure.
- Open access
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Multidrug-resistant Klebsiella pneumoniae infection causes immune activation, macrophage heterogeneity, and fibrosis in porcine lungs at single-cell resolution.
- Open access
Salmonella overcomes colonization resistance by disrupting microbiota, inducing inflammation, and damaging the intestinal barrier, promoting chronic infection.
Itaconate inhibits pathogen metabolism and reprograms host immunity, with potential therapeutic applications in infection, as evidenced by preclinical studies.
AKAV reprograms host mRNA granules and translation machinery to enhance its cap-snatching efficiency, with PKR-eIF2α signaling playing a central role.
- Open access
Long noncoding RNA MAPKAPK5-AS1 is essential for HBV cccDNA formation by modulating NABP1 expression in infected cells.
Giardia intestinalis exhibits genetic diversity and employs multiple virulence mechanisms, including antigenic variation and extracellular vesicle release, to persist in hosts.
- Open access
Enterovirus 2B functions as a membrane stress sensor coordinating multiple cell death pathways, not just as a viroporin, with conformational dynamics linked to calcium signaling and immune evasion.
Gut microbiota and metabolites in PWHIV with MASLD show significant alterations, with a random forest model achieving an AUC of 0.819 for discrimination.
Quorum sensing regulates bacterial secretion systems that deliver antifungal effectors, with T6SS disrupting fungal cell integrity and T3SS mediating mutualistic and antagonistic interactions.
Integrated multi-omics analysis reveals PPAR signaling network associations with lipid metabolism alterations and intestinal injury in PDCoV-infected piglets.
Hcp1, an in vivo-upregulated virulence determinant, has been successfully developed into a point-of-care test with 88.3% sensitivity and 86.1-100% specificity for melioidosis diagnosis.
Clade Ib and Clade IIb.A.2.1 monkeypox virus variants cause similar disease severity in a rabbit model, with both inducing skin and testicular lesions.
Polystyrene nanoplastics and Helicobacter pylori co-internalization in gastric cancer cells modulate metastasis and carcinogenesis processes, with PS-NPs alone promoting metastasis in vivo.
E. citroniae and related gut microbiome species produce small molecules that inhibit V. cholerae motility and induce biofilm formation, affecting its behavior.
Prevotella intermedia culture supernatant increases Mycobacterium avium burden by impairing alveolar macrophage antimicrobial functions in mice.
Fungal cell wall polysaccharides are recognized by immune receptors, shaping antifungal responses and immunopathology, with recognition mechanisms and immune roles varying by context.
Damage-Response Framework shows disease outcomes depend on host immune response, with parasite survival and damage varying across infections.
- Open access
- 1 cites
Endogenous RNA virus-derived elements in Bombyx mori exhibit distinct roles in development and virus susceptibility, with BmChuEVE3 and BmToEVE showing contrasting effects.
- Open access
Four distinct phenotypes of phage resistance, including complete and partial resistance, were identified in hypervirulent carbapenem-resistant Klebsiella pneumoniae under phage Kpph1 pressure.
- Open access
Uv7366, an apoplastic glycoside hydrolase in Ustilaginoidea virens, enhances virulence on rice and triggers plant immune responses, with deletion reducing pathogen virulence.
Mechanical cues sensed by the ZraSR two-component system activate type 1 fimbriae in E. coli K1, promoting meningitis in neonatal models.
Ascaris suum infection causes lasting changes in pig gut microbiome and metabolite profiles, including a 79% increase in histamine production after fenbendazole treatment.
α2,6-sialylation of Integrin β3 by ST6Gal1 is essential for human cytomegalovirus entry into fibroblasts, with absence reducing viral internalization by impairing receptor interactions.
MoCul4 enhances MoKmt1-mediated H3K9 methylation and is essential for growth, development, and pathogenicity in Magnaporthe oryzae, with Δ Mocul4 mutants showing more severe defects.
Penicillium overgrowth and microbial imbalance are linked to fruiting body abortion in artificially cultivated Chinese cordyceps, with Penicillium enrichment correlating with developmental failure.
- Open access
Fucosylated hemocyanin enhances shrimp antibacterial immunity by regulating ER stress and AMP production, reducing Vibrio parahaemolyticus loads in vivo.
Coxiella burnetii forms a small cell variant-like persistent form under hypoxia, increasing infectivity, antibiotic tolerance, and resistance to immune clearance.
Genomic, regulatory, and metabolic factors collectively constrain host specialization in Magnaporthe oryzae lineages, explaining their stability and rare host shifts.
Mosquito gut microbiota-based strategies reduced dengue incidence by up to 86.2%, offering a promising alternative to traditional control methods hindered by resistance and vaccine limits.
Eight closely related ST11-KL64 carbapenem-resistant Klebsiella pneumoniae strains evolved within a host, with the last strain showing greater host adaptability and recurrent infection potential.
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Journals this month
- bioRxiv6244
- medRxiv1789
- PNAS447
- Sci Adv354
- JAMA268
- Environ Res246
- BMJ196
- Nat Commun173
- Environ Pollution167
- Nature151
- Applied & Environ Microbio145
- Science141
- Lancet128
- Cell Rep127
- NEJM119
- Plant Cell Environ118
- J Exp Bot107
- mBio107
Topics moving, week to 22 Oct 2026
- Single-cell and spatial transcriptomics6
- Neuroinflammation and Neurodegeneration Mechanisms5
- Cancer Immunotherapy and Biomarkers5
- Gut microbiota and health5
- Cancer Genomics and Diagnostics4
- Bacteriophages and microbial interactions4
- CAR-T cell therapy research3
- Lung Cancer Treatments and Mutations3
- Liver Disease Diagnosis and Treatment3
- Dementia and Cognitive Impairment Research3