mSystems
American Society for Microbiology · Microbiology & Mycology · ISSN 2379-5077
- Impact (2-yr)
- 6.5
- h-index
- 119
- Open access
- 100%
- Works
- 3.1K
- Papers this month
- 59
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Genomic analysis of 253 Cambodian Burkholderia pseudomallei isolates reveals high diversity, 11 distinct clades, and a unique gene-containing genomic island.
- Open access
Extended-spectrum and last-resort β-lactams cause more pronounced shifts in manure-derived microbiomes and resistomes than ampicillin in an in vitro model.
- Open access
GapC and GapD are substrate-specific auxiliary enzymes that contribute to redox balancing and metabolic module integration in Pseudomonas putida KT2440.
- Open access
Two candidate type XI-like retron lineages with unique architectures and accessory modules were identified across diverse microbial habitats in the SPIRE metagenome collection.
Distinct carbon sources induce different metabolic states in Propionibacterium freudenreichii, with lactate supporting high vitamin B12 yields and hexoses causing redox constraints.
Fungal dormancy involves diverse structures with complex morphophysiological features that are comparable to bacterial dormant cells, highlighting shared survival strategies across microbes.
Proteomic profiling reveals that the (p)ppGpp-mediated stringent response in Pseudomonas aeruginosa regulates over 339 proteins during stationary phase, highlighting extensive metabolic shutdown and stress adaptation.
- Open access
Parasite-associated microbiomes in Ascaris lumbricoides and Trichuris trichiura are largely transient, host-derived communities acquired through horizontal transmission, with potential roles in parasite survival.
Gut microbial families Lachnospiraceae and Oscillospiraceae are enriched in non-MASH mice and linked to lower fatty acids before histologic MASH onset.
Disruption of 52 genes, including prophage-associated loci, is linked to loss of S. aureus survival under vancomycin at its minimum inhibitory concentration.
A Pseudomonas trivialis strain from threespine stickleback guts shows evidence of polypropylene surface oxidation in monoculture.
Cellular responsiveness in Pseudomonas putida KT2440 decreases with benzoate exposure and predicts population collapse in continuous cultures.
Continuous cultivation in bioreactors reveals diverse infection patterns and host adaptation dynamics of Minisyncoccota episymbionts.
Gut microbiome alterations, especially enrichment of Veillonella atypica, are strongly linked to hepatitis E severity with an AUC of 0.944 in discriminating patients from controls.
All biosynthetic gene clusters in Saccharomonospora xinjiangensis XJ-54 show growth-phase-dependent transcriptional activity, producing antifungal metabolites through coordinated biosynthetic programs.
Synthesis-driven reverse metabolomics identified 334 new 3-hydroxy N-acyl amides across 54,744 datasets, confirming their widespread presence in human biological samples.
A novel human gut-derived Streptomyces strain, CGMCC 17111, exhibits potent suppressive effects on colorectal cancer without causing inflammatory reactions.
Thirty years of prescribed fire in the Albany Pine Bush significantly depletes soil nitrate and reduces nitrogen-cycling microbial functions related to greenhouse gas emissions.
Carbon starvation induces extensive proteomic remodeling in Mycobacterium abscessus, with 33% of the proteome showing significant changes under non-replicating conditions.
Comparative genomics and metabolomics reveal context-dependent biosynthetic potential in Hyaloscypha finlandica, a Populus-associated dark septate endophyte, with 41 biosynthetic gene clusters identified.
Mycobacterium tuberculosis genomes in macaques reveal distinct evolutionary paths under ART and SIV coinfection, with ART associated with oxidative damage variants.
Microbial diversity and nitrogen cycling in the eastern tropical Pacific OMZs show minimal interannual variation between two La Niña years despite ENSO fluctuations.
A candidate 19-species gut microbiome signature, with Firmicutes bacterium CAG:41 as the only threshold-stable taxon, is depleted in colorectal cancer, Crohn's disease, and liver cirrhosis.
Tryptophan supplementation induces metabolomic shifts in Acidobacteriaceae, producing phytohormones and antifungal metabolites linked to soil health.
Pairwise SNP clustering with low thresholds often produces non-monophyletic tuberculosis clusters in high-burden, endemic settings like Thailand, challenging its reliability.
Glutathione acts as an exometabolite that promotes growth recovery in S. pombe mutants with defects in amino acid metabolism and cell morphology.
Chinese CC398 predominantly comprises human-associated MSSA lineages with unique East Asia-specific phylogroups, contrasting with the livestock-associated MRSA lineages in Western countries.
Non-genetic variation in red blood cell hemoglobin content modulates nutrient consumption by Plasmodium falciparum, with infected cells amplifying this variability to over 100%.
- Open access
RNA-based library preparation provides the most comprehensive recovery of the clinical infectome, especially for RNA viruses, cellular pathogens, and host immune signals.
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Journals this month
- bioRxiv6244
- medRxiv1789
- PNAS447
- Sci Adv354
- JAMA268
- Environ Res246
- BMJ196
- Nat Commun173
- Environ Pollution167
- Nature151
- Applied & Environ Microbio145
- Science141
- Lancet128
- Cell Rep127
- NEJM119
- Plant Cell Environ118
- J Exp Bot107
- mBio107
Topics moving, week to 22 Oct 2026
- Single-cell and spatial transcriptomics6
- Neuroinflammation and Neurodegeneration Mechanisms5
- Cancer Immunotherapy and Biomarkers5
- Gut microbiota and health5
- Cancer Genomics and Diagnostics4
- Bacteriophages and microbial interactions4
- CAR-T cell therapy research3
- Lung Cancer Treatments and Mutations3
- Liver Disease Diagnosis and Treatment3
- Dementia and Cognitive Impairment Research3