Nerve injury and regeneration

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Self-organizing human dual neural organoids model regional disease defects and teratogenicity.
Developmental Cell · 14 Oct 2026 · Journal Article
Human peripheral-central dual neural organoids (hPCOs) reveal bidirectional Wnt signaling roles in neurodevelopment, modeling nociceptor defects and teratogenic risks.
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Voluntary engagement predicts recovery across rehabilitation time points after experimental spinal cord injury
bioRxiv · 8 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.28.751615
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A human-induced pluripotent stem cell-derived spheroid model to investigate myelin injury and repair.
Nature Neuroscience · 1 Oct 2026 · Journal Article
A human iPSC-derived spheroid model reveals that remyelinated axons have thinner myelin sheaths after injury, advancing understanding of human myelin repair mechanisms.
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https://jclub.com.au/a/42823475
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Stem cells help restore hand function after spinal cord injury in monkeys.
Nature Biotechnology · 1 Oct 2026 · Journal Article
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https://jclub.com.au/a/41249837
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Extensive restoration of forelimb function in primates with spinal cord injury by neural stem cell transplantation.
Nature Biotechnology · 1 Oct 2026 · Journal Article
Neural stem cell transplantation from human embryonic stem cells improves forelimb function by 9.2-fold in hemisected primates with spinal cord injury.
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https://jclub.com.au/a/41249838
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Culture and gene expression profiling of Schwann cells from human sural nerve.
Communications Biology · 28 Sept 2026 · Journal Article
A protocol enables reproducible culture and transcriptome analysis of human Schwann cells from small sural nerve biopsies, facilitating PNP research.
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https://jclub.com.au/a/42816520
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Cell Type-Specific Structural and Functional Signatures of APOE4, Age and Sex in the Mouse Anterior Olfactory Nucleus
bioRxiv · 26 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.21.753183
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A tribenzamide small molecule with retinoic acid-like activity promotes axon growth and motor recovery after spinal cord injury.
bioRxiv · 11 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.11.05.686894
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β-catenin controls Afadin cortical recruitment to regulate planar epithelial cell division
bioRxiv · 5 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.10.23.684278
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An iPSC-derived neural progenitor cell therapy for subacute spinal cord injury: a phase 1 trial with long-term follow-up.
Nature Medicine · 1 Sept 2026 · Clinical Trial, Phase I
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https://jclub.com.au/a/42481854
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RhoA in postnatal spinal motoneuron is essential for peripheral myelination.
Communications Biology · 1 Sept 2026 · Journal Article
RhoA in postnatal spinal motoneurons is crucial for peripheral myelination, with its absence causing significant hypomyelination in mice.
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https://jclub.com.au/a/42760283
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A Systematic Review and Independent Benchmarking of Automated Nerve Morphometry Methods
bioRxiv · 31 Aug 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.06.15.731646
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In vivo virus-free lineage tracing and live imaging 1 reveal that NeuroD1 does not reprogram microglia into neurons
bioRxiv · 27 Aug 2026 · Preprint
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