Lipid Membrane Structure and Behavior

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Local Confinement within Plasma Membrane Nanodomains Promotes Constitutive Activity of GPCRs
bioRxiv · 22 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.02.17.706370
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A molecular safeguard in Escherichia coli Braun's lipoprotein (Lpp) biogenesis.
mBio · 14 Oct 2026 · Journal Article
DcrB acts as a molecular safeguard in Escherichia coli by promoting Lpp maturation and preventing toxic inner membrane-peptidoglycan linkages, especially under stress conditions.
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Mammalian MemPrep establishes the lipid composition of ER membranes in HEK293T cells.
EMBO Reports · 14 Oct 2026 · Journal Article
Mammalian ER membranes are primarily composed of phosphatidylcholine and monounsaturated glycerophospholipids, indicating a highly compressible bilayer.
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Cyclical content exchange in hydrogel-core synthetic cells
bioRxiv · 13 Oct 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.07.16.665112
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Structural model of the blood protein vitronectin bound to lipid and HDL
bioRxiv · 13 Oct 2026 · Preprint
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Myristoylation licenses disordered viral VP4 protein to anchor to and perforate the membrane through phase separation
bioRxiv · 7 Oct 2026 · Preprint
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Non-redundant cardiolipin synthase family proteins shape lipid composition and stress resilience in Bacteroides fragilis
bioRxiv · 6 Oct 2026 · Preprint
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The Staphylococcus aureus carotenoid staphyloxanthin modifies the structure of phosphatidylglycerol lipid bilayers
bioRxiv · 6 Oct 2026 · Preprint
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GalaxyMemMD: an end-to-end Galaxy toolset for reproducible membrane embedding, molecular dynamics simulation, and analysis of membrane proteins
bioRxiv · 4 Oct 2026 · Preprint
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Structural basis of selective phospholipid recognition and local membrane deformation by CTL1
bioRxiv · 3 Oct 2026 · Preprint
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Curvature sensing and generation by diverse membrane-tethered polymers can be explained by a unifying physical model
bioRxiv · 2 Oct 2026 · Preprint
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Distinct Aβ40 and Aβ42 co-assembly pathways with free lipids: Experiment-driven MD study
bioRxiv · 2 Oct 2026 · Preprint
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Mechanical regulation of endocytosis by protein droplet capillary forces
bioRxiv · 2 Oct 2026 · Preprint
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Author Correction: When membrane proteins prefer lipids.
Nature Chemical Biology · 1 Oct 2026 · Published Erratum
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HoT self-blinking probes for chromatin imaging.
Nature Reviews Molecular Cell Biology · 1 Oct 2026 · Journal Article
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Phosphoglycerate kinase 1 cooperates with the AP2 complex to promote endocytosis.
EMBO Reports · 1 Oct 2026 · Journal Article
Phosphoglycerate kinase 1 (PGK1) forms a novel coat protein complex with AP2, promoting endocytosis by acting as a cargo adaptor and stabilizer of the AP2 complex.
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The class VIII myosin ATM2 stabilizes actin-plasma membrane contacts in tobacco pollen tubes by locally promoting PtdIns(4,5)P(2) formation.
Nature Plants · 1 Oct 2026 · Journal Article
ATM2 stabilizes actin-PM contacts in tobacco pollen tubes by locally promoting PtdIns(4,5)P2 nanodomain formation, affecting actin dynamics and pollen tube morphology.
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The lipidomic architecture of the mouse brain.
Nature · 1 Oct 2026 · Journal Article
Mapping the adult mouse brain reveals a lipidomic architecture with fine-grained biochemical structure that aligns with functional anatomy and varies across regions and physiological states.
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ATP8B1-TMEM30B Flippase Activity Maintains Stereocilia Lipid Asymmetry Required for Hearing
bioRxiv · 30 Sept 2026 · Preprint
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Sphingolipids associate with the chlamydial nucleoid and mark developmental transitions in Chlamydia trachomatis.
Nature Communications · 30 Sept 2026 · Journal Article
Sphingolipids localize within Chlamydia trachomatis nucleoids and mark early developmental transitions, with sphingomyelin linked to DNA condensation in elementary bodies.
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Geometry-Controlled Diffusion in Bicontinuous Cubic Lipid Net-works: Network Topology, Tortuosity, and Pore-Scale Constric-tion Effects
bioRxiv · 27 Sept 2026 · Preprint
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Plasmodium berghei is resistant to aryl amino acetamides that inhibit P. falciparum growth by targeting the phospholipid transfer protein PfSTART1.
bioRxiv · 26 Sept 2026 · Preprint
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Clathrin adaptors drive phase separation in endocytosis and trafficking.
Communications Biology · 26 Sept 2026 · Journal Article
Yeast adaptors Ent5 and Sla2 undergo LLPS, with Ent5's disordered helix and Sla2's coiled-coil region mediating condensate formation.
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Extreme envelope plasticity drives temperature-dependent morphogenesis in the LPS-free bacterium Sphingobium yanoikuyae
bioRxiv · 25 Sept 2026 · Preprint
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Negative feedback of cyclic di-GMP levels optimizes switching between sessile and motile lifestyles in Vibrio cholerae
bioRxiv · 22 Sept 2026 · Preprint
Negative feedback regulation of cyclic di-GMP levels via VpsR and CdgC optimizes V. cholerae's transition between motile and biofilm states.
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https://jclub.com.au/a/10.1101/2024.09.01.610008
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Actin-membrane interface stress regulates Arp2/3-branched actin density during lamellipodial protrusion
bioRxiv · 20 Sept 2026 · Preprint
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TRIM62 facilitates influenza A virus entry by regulating WASH-dependent endosomal trafficking.
EMBO Reports · 19 Sept 2026 · Journal Article
TRIM62 promotes influenza A virus entry by preventing WASH from associating with retromer, enhancing endosomal trafficking necessary for viral internalization.
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Structure-Dependent Effects of Lipid Conjugation on Cytosolic Accumulation in Escherichia coli and Mammalian Cells
bioRxiv · 18 Sept 2026 · Preprint
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Pseudomonas aeruginosa: a model system for studying the behavior of unbiased flagellar motors.
Journal of bacteriology · 17 Sept 2026 · Review
Pseudomonas aeruginosa's flagellar motor operates with near-unbiased rotation, modulating dwell times rather than bias, revealing a novel chemotaxis mechanism.
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FlgJ cell-wall hydrolyzing activity enhances, but is not required, for flagellum assembly in Salmonella enterica.
Journal of bacteriology · 17 Sept 2026 · Journal Article
Salmonella enterica can assemble functional flagella without FlgJ’s cell-wall hydrolyzing activity, though at reduced efficiency, demonstrating diverse flagellar assembly mechanisms.
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