Liver physiology and pathology
Moving in bioRxiv, Journal of hepatology, Gut, The lancet. Gastroenterology & hepatology, Gastroenterology, Nature Communications, Nature reviews. Gastroenterology & hepatology and Blood.
- Moved, week to 23 Oct 2026
- 0
- Papers in 60 days
- 33
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Moved this week
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Latest in Liver physiology and pathology
Newest first · last 60 days
Combining LGR5- and MET-targeting ADCs with different payloads significantly delays tumor relapse and prolongs survival in preclinical colorectal cancer models.
- Open access
Pectin reduces alcohol-associated liver disease in female mice through activation of AhR across multiple cell types, despite cell-specific AhR deficiencies.
- Open access
ZFP36L1, a zinc-dependent RNA-binding protein, suppresses hepatocyte senescence and ALD progression by destabilizing p21 and JAG1 mRNAs in mice and humans.
- Open access
- 1 cites
Blood-based biomarkers show promise for liver cancer but require further validation before widespread clinical use.
Advances in surgical planning and molecular understanding are expanding the resectability of liver cancers, including hepatocellular carcinoma and intrahepatic cholangiocarcinoma.
- 1 cites
Actin cytoskeletal dynamics are crucial for hepatic myofibroblast activities involved in liver fibrosis.
Hepatocytes support pancreatic cancer liver metastasis by producing serine through a CXCL5-CXCR2-driven pathway, promoting tumor growth in the liver.
- Open access
Canonical Notch2 signaling is essential for the development, maintenance, and function of iron-recycling macrophages, with its disruption causing iron overload in mice.
- Open access
Multi-organelle signatures identified distinct cell states and metabolic adaptations in liver and pancreas tissues, revealing complex intra-zonal heterogeneity and stress responses.
Reverse bioengineering of liver-on-a-chip systems reveals developmental principles that outperform current models, with 80% of key developmental features captured.
- Open access
Vascular macrophage dysfunction causes bacterial translocation in cirrhosis, with 20-week murine models showing impaired gut-vascular interactions and increased systemic bacterial spread.
- Open access
- 10 cites
Pharmacological plasminogen reduction significantly enhances liver regeneration and decreases posthepatectomy liver failure in mice and humans, with tranexamic acid showing clinical promise.
- Open access
A spatial transcriptomics atlas reveals hypertranscription and distinct regenerative cell populations during mouse jejunum repair after radiation injury.
- Open access
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Journals this month
- bioRxiv6157
- medRxiv1716
- PNAS447
- Sci Adv354
- JAMA262
- Environ Res230
- BMJ182
- Environ Pollution165
- Nat Commun161
- Science141
- Nature138
- Lancet128
- Cell Rep120
- NEJM119
- mBio107
- Plant Cell Environ107
- Curr Biol106
- J Exp Bot106
Topics moving, week to 23 Oct 2026
- Single-cell and spatial transcriptomics6
- Neuroinflammation and Neurodegeneration Mechanisms5
- Bacteriophages and microbial interactions5
- Gut microbiota and health5
- Genomics and Phylogenetic Studies4
- Cancer Genomics and Diagnostics4
- Cancer Immunotherapy and Biomarkers4
- Alzheimer's disease research and treatments3
- Inflammatory Bowel Disease3
- Influenza Virus Research Studies3