Cell Adhesion Molecules Research

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Human organ chip models recapitulate FRC-driven high endothelial venule differentiation, immune recruitment, and cancer-induced disruption.
Cell Reports · 13 Oct 2026 · Journal Article
Human organ chip models demonstrate FRC-driven HEV differentiation, immune recruitment, and cancer-induced disruption, with FRCs promoting HEV marker expression and structural features.
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Spatial clustering of adhesion-deficient cells delaysclearance and prolongs geometric unjammingsignatures in epithelial tissues
bioRxiv · 7 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.06.08.730803
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Z-DNA Reveals a Conformational Dimension of Neutrophil Extracellular Trap Organization
bioRxiv · 3 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.05.04.722750
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The Par complex regulates apical-basal cell polarity through modulation of FAK signaling homeostasis
bioRxiv · 2 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.05.03.722465
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The Alzheimer's Disease-associated gene CD2AP regulates permeability of endothelial cells and transendothelial migration of immune cells
bioRxiv · 2 Oct 2026 · Preprint
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A single-chain derivative of an integrin-activating antibody potentiates organoid growth in Matrigel and collagen hydrogels.
Nature Biotechnology · 1 Oct 2026 · Journal Article
A single-chain antibody derivative of TS2/16 enhances gastrointestinal organoid yield up to fivefold in Matrigel and six- to sevenfold in collagen I hydrogels.
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https://jclub.com.au/a/41152624
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Immune cells go with the tissue flow.
Nature Cell Biology · 1 Oct 2026 · Journal Article
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Nanoscale Structural and Functional Impacts of Disease-Associated Collagen Mutations
bioRxiv · 25 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.09.03.673992
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Tumour-derived LAMA5 is critical for tumour initiation and controls progression and phenotype in luminal breast cancer
bioRxiv · 25 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2024.12.26.630367
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Polystyrene nanoplastics exacerbate systemic lupus erythematosus via neutrophil extracellular traps (NETs) formation.
Environmental pollution · 15 Sept 2026 · Journal Article
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https://jclub.com.au/a/42251929
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Reduced platelet formation associated with serine metabolic dysregulation in integrin αIIbβ3-deficient megakaryocytes.
Blood · 10 Sept 2026 · Journal Article
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Foetal Bovine Serum as a Critical Hidden Variable in Neutrophil - Biomaterial Studies
bioRxiv · 10 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.11.10.687474
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Polyanionic peptibody ameliorates tau pathology and promotes neuronal proteostasis in a tau transgenic mouse model
bioRxiv · 9 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.08.13.665777
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CD239 deficiency in distal tubules impairs cell polarity and increases susceptibility to renal injury
bioRxiv · 8 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.05.31.728029
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Extravascular coagulation stabilizes pro-fibrotic stromal states via tumor-intrinsic PAR1 signaling in pancreatic ductal adenocarcinoma
bioRxiv · 3 Sept 2026 · Preprint
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A Co-opted Developmental Gene Regulatory Program in Endothelial Progenitors Promotes Tumor Angiogenic Phenotypes.
Cancer Research · 2 Sept 2026 · Journal Article
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https://jclub.com.au/a/42258673
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P-selectin delineates conserved functional heterogeneity in early hematopoietic stem cell aging in humans and mice.
EMBO Journal · 1 Sept 2026 · Journal Article
P-selectin marks early functional heterogeneity in aging hematopoietic stem cells, with high expression linked to increased DNA damage and myeloid bias in humans and mice.
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Endothelial cell-intrinsic NOD2 signaling regulates the intestinal immune response through the generation of effector and memory T cells.
Nature Immunology · 1 Sept 2026 · Journal Article
Endothelial cell-intrinsic NOD2 signaling is essential for T cell recruitment and immune memory formation in the intestine, with NOD2 driving effector and memory T cell accumulation.
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https://jclub.com.au/a/42477058
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Engineering Stapled Peptide Inhibitors Reveals Design Principles for Targeting Talin-Induced Integrin Activation
bioRxiv · 31 Aug 2026 · Preprint
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De novo E-cadherin/catenin complex formation controls basal epithelial mechanics and force transmission for apoptotic cell clearance.
Nature Communications · 27 Aug 2026 · Journal Article
De novo E-cadherin/catenin complex formation at the basal epithelial surface enables force transmission and efficient apoptotic cell clearance in zebrafish and mice.
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A microexon confers functional divergence of the actin nucleator Arp2/3
bioRxiv · 26 Aug 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.10.12.681909
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Oncogene-Mechanics Axis: KRAS G12C Confers Agility Enabling Malignant Mechano-responses to Peristalsis in Colorectal Cancer
bioRxiv · 25 Aug 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.04.28.721453
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