Cardiovascular Function and Risk Factors

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Prognostic impact of late left ventricular reverse remodeling in heart failure with reduced ejection fraction
medRxiv · 22 Oct 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.10.10.25337780
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Mitochondrial instability contributes to IFN-driven heart disease.
bioRxiv · 14 Oct 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.09.15.674036
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Polygenic risk of cardiovascular disease manifests in cardiac structure and function
medRxiv · 12 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.06.07.26354998
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WITHDRAWN: How to Detect the Early Cardiac Functional Change and Predict Heart Failure in Paroxysmal Atrial Fibrillation? A Prospective Cohort Study
medRxiv · 9 Oct 2026 · Preprint
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https://jclub.com.au/a/10.1101/2024.06.26.24309561
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Tricuspid-Valve Intervention in Heart Failure.
New England Journal of Medicine · 8 Oct 2026 · Randomized Controlled Trial
Transcatheter tricuspid-valve repair significantly improves outcomes in patients with severe tricuspid regurgitation, with a win ratio of 2.42 favoring repair at 1 year.
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https://jclub.com.au/a/42670975
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Gcn5l1 governs heart-to-liver crosstalk in cardiometabolic heart failure by modulating cholesterol metabolism
bioRxiv · 6 Oct 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.02.05.636634
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Metabolic Perturbation Exacerbates Sinoatrial Node Dysfunction in Heart Failure
bioRxiv · 2 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.02.06.704519
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Propelling MASLD trials into the era of non-invasive tests.
The lancet. Gastroenterology & hepatology · 1 Oct 2026 · Journal Article
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https://jclub.com.au/a/42285115
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Cardiovascular magnetic resonance reference ranges and centile-based categories for atrial and ventricular cardiac structure and function: 2026 Update from the Healthy Hearts Consortium
medRxiv · 30 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.04.07.25325351
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Multi-omics insight into cardiac myofibril remodeling in post-prandial Burmese pythons.
Communications Biology · 30 Sept 2026 · Journal Article
Post-prandial Burmese pythons show increased myofibril tension and relaxation rates, with frequent feeding linked to slower myofibril activation, indicating significant cardiac remodeling.
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https://jclub.com.au/a/42892626
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Left Ventricular Volume and Function Assessment Using a Reduced-Slice Approach in Cardiovascular Magnetic Resonance
medRxiv · 28 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.05.29.26354413
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New-Onset Heart Failure in Patients with Obesity using Tirzepatide or Semaglutide
medRxiv · 26 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.21.26363546
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Sotatercept Improves Right Heart Mechanics Despite Reduced Myocardial Contractility in Pulmonary Arterial Hypertension: A Prospective Exercise Hemodynamic Study.
Circulation · 22 Sept 2026 · Journal Article
Sotatercept reduces right ventricular contractility by 24 weeks in pulmonary arterial hypertension patients but maintains RV-PA coupling and improves overall right heart mechanics.
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https://jclub.com.au/a/42770225
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Multimodal data-driven clustering analysis of heart failure patients identifies two distinct patterns of heart failure with preserved ejection fraction: Results from the PACIFIC-PRESERVED study.
Nature Communications · 15 Sept 2026 · Observational Study
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https://jclub.com.au/a/42875459
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Complexity of Diagnosing Volume Overload.
JAMA · 1 Sept 2026 · Journal Article
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https://jclub.com.au/a/42377953
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Complexity of Diagnosing Volume Overload-Reply.
JAMA · 1 Sept 2026 · Journal Article
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https://jclub.com.au/a/42377972
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Complexity of Diagnosing Volume Overload.
JAMA · 1 Sept 2026 · Journal Article
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https://jclub.com.au/a/42377943
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Complexity of Diagnosing Volume Overload.
JAMA · 1 Sept 2026 · Journal Article
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https://jclub.com.au/a/42377986
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Complexity of Diagnosing Volume Overload.
JAMA · 1 Sept 2026 · Journal Article
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https://jclub.com.au/a/42377949
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Complexity of Diagnosing Volume Overload.
JAMA · 1 Sept 2026 · Journal Article
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https://jclub.com.au/a/42377968
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Timing of PCI in Patients Undergoing Transcatheter Aortic-Valve Implantation.
New England Journal of Medicine · 30 Aug 2026 · Journal Article
Performing TAVI before PCI is noninferior to PCI before TAVI regarding 1-year outcomes in patients with severe aortic stenosis and coronary artery disease, with a 22.2% versus 24.2% event rate.
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Heterogeneous Treatment Effects in HFpEF: Distinguishing Drug-Specific Response from Prognostic Phenotypes Across Randomized Trials
medRxiv · 28 Aug 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.07.06.26357251
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Association between sarcopenia and the risk of diabetic cardiomyopathy in patients with type 2 diabetes mellitus: a single-center retrospective cohort study.
Frontiers in Genetics · 25 Aug 2026 · Journal Article
Sarcopenia independently increases the risk of diabetic cardiomyopathy by 2.25 times in patients with type 2 diabetes mellitus.
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