Colorectal Cancer Screening and Detection

Moving in Gastroenterology, Gut, The lancet. Gastroenterology & hepatology, Nature Medicine, medRxiv, mSystems, Nature Reviews Cancer and New England Journal of Medicine.

Moved, week to 23 Oct 2026: 0
Papers in 60 days: 24

Add Colorectal Cancer Screening and Detection as an interest in JClubFree on iPhone and Android · interests shape Home, Discover and your digest

Rebuilt 23 October 2026 at 1:59 pm AEDT

Moved this week

Everything that moved →

Nothing in this topic has moved yet this week.

Latest in Colorectal Cancer Screening and Detection

Newest first · last 60 days

Novel adenoma-immune phenotypes are associated with risk of metachronous polyps and colorectal cancer in a bowel screening cohort
medRxiv · 16 Oct 2026 · Preprint
Adenoma immune profiles, especially CD3+ T cell density, predict future colorectal neoplasia with an odds ratio of 1.44 in a bowel screening cohort.
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/10.64898/2026.02.25.26346992
Open in JClub
Effect of Screening with Multicancer Early-Detection Test on Late-Stage Cancer Diagnosis.
New England Journal of Medicine · 8 Oct 2026 · Randomized Controlled Trial
Screening with multicancer early-detection blood tests did not significantly reduce the incidence of stage III or IV cancers after three rounds in a large randomized trial.
- 2 cites
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42776074
Open in JClub
Implementing discard strategies for diminutive polyps using autonomous CADx in clinical practice.
Gut · 7 Oct 2026 · Journal Article
Read the AI summary in JClub
- 6 cites
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/40750337
Open in JClub
Endoscopic intermuscular dissection for rectal cancer: are we ready to skip surgery?
Gut · 7 Oct 2026 · Letter
Read the AI summary in JClub
- Open access
- 4 cites
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/40681325
Open in JClub
Gut microbiome signatures in colorectal neoplasia: a cross-sectional study across neoplasia stages and subtypes.
Gut · 7 Oct 2026 · Multicenter Study
Gut microbiome signatures are weakly associated with colorectal neoplasia and do not serve as robust early biomarkers in a large cross-sectional study.
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/41791848
Open in JClub
Preclinical stages of Crohn's disease defined by faecal calprotectin in asymptomatic first-degree relatives: screening framework for prevention trials.
Gut · 7 Oct 2026 · Journal Article
Persistent elevation of faecal calprotectin >70 µg/g in asymptomatic first-degree relatives predicts presymptomatic Crohn's disease with 89% sensitivity and 94% specificity.
- 6 cites
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/41381180
Open in JClub
Response to 'Rectal versus colonic submucosal cancer rates and procedural outcomes in large non-pedunculated polyps: French ESD registry data'.
Gut · 7 Oct 2026 · Letter
Read the AI summary in JClub
- 1 cites
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/41381177
Open in JClub
Prevention of colorectal cancer through screening for advanced precancerous lesions: are blood-based tests the answer?
The lancet. Gastroenterology & hepatology · 1 Oct 2026 · Journal Article
Read the AI summary in JClub
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42575120
Open in JClub
Performance and safety of a multi-cancer early detection test: the PATHFINDER 2 study.
Nature Medicine · 1 Oct 2026 · Clinical Trial
The multi-cancer early detection (MCED) test in the PATHFINDER 2 study achieved a cancer detection rate of 0.54% among participants aged 50 or older, with a CSO prediction accuracy of 91.3%.
- Open access
- 2 cites
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42773207
Open in JClub
Performance of a multi-cancer early detection test in the randomized controlled NHS-Galleri trial.
Nature Medicine · 1 Oct 2026 · Randomized Controlled Trial
The multi-cancer early detection test in the NHS-Galleri trial detected primary cancers in 0.40% to 0.60% of participants across three screening rounds.
- Open access
- 1 cites
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42773209
Open in JClub
Artificial intelligence-assisted detection and optical differentiation of colorectal lesions in Lynch syndrome surveillance (CADLY2): a multicentre, open-label, randomised controlled superiority trial.
The lancet. Gastroenterology & hepatology · 1 Oct 2026 · Multicenter Study
AI-assisted colonoscopy did not significantly increase adenoma detection rate in Lynch syndrome surveillance, with a difference of 2.9% (p=0.41) in a multicentre trial.
- Open access
- 1 cites
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42462747
Open in JClub
A blood-based test for detection of advanced adenomas and colorectal cancer (DENEB): a multicentre diagnostic accuracy study.
The lancet. Gastroenterology & hepatology · 1 Oct 2026 · Multicenter Study
A blood-based assay detects colorectal cancer and advanced adenomas with 95% accuracy in a multicentre study, showing 91% sensitivity for colorectal cancer and 81% for advanced adenomas.
- 1 cites
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42575119
Open in JClub
Reply.
Gastroenterology · 1 Oct 2026 · Letter
Read the AI summary in JClub
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42309259
Open in JClub
APC Mosaicism: The Limited Utility of Ancillary Testing in Normal Colonic Mucosa.
Gastroenterology · 1 Oct 2026 · Letter
Read the AI summary in JClub
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42309261
Open in JClub
Nonadvanced Adenoma Number and Size as Predictors of Metachronous Advanced Colorectal Neoplasm: Implications for Surveillance Guidelines.
Gastroenterology · 1 Oct 2026 · Journal Article
Having 5 to 10 nonadvanced adenomas is linked to a 10.1% 5-year risk of advanced colorectal neoplasm, the highest among studied groups.
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42142544
Open in JClub
A Randomized Trial of Colonoscopy Versus Fecal Immunochemical Testing Versus Usual Care in the Detection of Colorectal Cancer.
Gastroenterology · 1 Oct 2026 · Journal Article
Read the AI summary in JClub
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42070696
Open in JClub
Shaping the future of early-onset colorectal cancer prevention.
Nature Reviews Cancer · 1 Oct 2026 · Review
Early-onset colorectal cancer (EOCRC) under age 50 is increasing globally, with lifestyle and early-life gut microbial exposures linked to its rise.
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42649278
Open in JClub
Integrative microbiome-methylome analysis links bacterial taxa to colorectal cancer histological subtypes.
mSystems · 22 Sept 2026 · Journal Article
Read the AI summary in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42635437
Open in JClub
Precision prevention and early detection: framework for a new clinical cancer control pathway.
The Lancet · 18 Sept 2026 · Review
Read the AI summary in JClub
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42759527
Open in JClub
Response to: 'Rectal versus colonic submucosal cancer rates and procedural outcomes in large non-pedunculated polyps: French ESD registry data' by Van der Voort et al.
Gut · 7 Sept 2026 · Letter
Read the AI summary in JClub
- 2 cites
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/41314787
Open in JClub
Presentation of the AGA William Beaumont Prize in Gastroenterology to Stuart Jon Spechler, MD, AGAF.
Gastroenterology · 3 Sept 2026 · Editorial
Read the AI summary in JClub
- Open access
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42695955
Open in JClub
A decade of artificial intelligence in endoscopy: from proof of concept to clinical reality.
The lancet. Gastroenterology & hepatology · 1 Sept 2026 · Journal Article
Read the AI summary in JClub
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42556365
Open in JClub
Interventions for Increasing Colorectal Cancer Screening Uptake: A Systematic Review and Network Meta-Analysis.
Gastroenterology · 1 Sept 2026 · Systematic Review
Patient navigation and mailed FIT outreach significantly increase colorectal cancer screening uptake, especially in populations with low baseline rates, with risk ratios of 1.58 and 1.36 respectively.
- 2 cites
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/41932450
Open in JClub
Prevalence of APC Somatic Mosaicism and Colibactin Exposure in Patients With Unexplained Colorectal Adenomatous Polyposis.
Gastroenterology · 26 Aug 2026 · Journal Article
Read the AI summary in JClub
Open
Share
Post on X Post on Bluesky Share on LinkedIn
https://jclub.com.au/a/42648446
Open in JClub

Add Colorectal Cancer Screening and Detection as an interest in JClub

Journals this month

All journals →

Topics moving, week to 23 Oct 2026

All topics →

By field

All journals by field →

Moved this week

Latest in Colorectal Cancer Screening and Detection

Browse JClub