G4All provides the first comprehensive, curated database of experimentally validated G-quadruplex-forming DNA and RNA sequences with negative controls.
- Open access
DNA and Nucleic Acid Chemistry
Moving in Nucleic Acids Research.
- Moved, week to 23 Oct 2026
- 1
- Papers in 60 days
- 28
Add DNA and Nucleic Acid Chemistry as an interest in JClubFree on iPhone and Android · interests shape Home, Discover and your digest
Rebuilt
Moved this week
Latest in DNA and Nucleic Acid Chemistry
Newest first · last 60 days
G4All provides the first comprehensive, curated database of experimentally validated G-quadruplex-forming DNA and RNA sequences with negative controls.
- Open access
Stabilizing G-quadruplexes with pyridostatin reduces NF-κB-dependent inflammatory gene expression in lipopolysaccharide-stimulated mouse macrophages.
- Open access
G4SCOPE accurately predicts chromatin G-quadruplex occupancy and epigenetic features from primary DNA sequences, revealing distinct G4 subclasses linked to specific methylation landscapes.
- Open access
VIPR systems achieve precise DNA targeting through noncontiguous triplex formation, with 21 cryo-EM structures revealing the mechanism of target engagement.
- 2 cites
IMP-2380 effectively inhibits the NorA efflux pump in Staphylococcus aureus, restoring antibiotic susceptibility with low-nanomolar potency and structural trapping of the transporter.
- Open access
A BAC-based non-infectious SARS-CoV-2 replicon identified the M gene as a promising antisense target with an EC50 of 6.3 nM for antiviral development.
- Open access
E. coli RNA polymerase can efficiently transcribe an eight-letter genetic alphabet, including two orthogonal unnatural base pairs, with high fidelity and structural compatibility.
- Open access
POLE exonuclease deficiency causes synthetic lethality in highly aneuploid cancer cells, revealing a potential targeted therapy approach.
- Open access
High-resolution imaging reveals complex, dynamic architecture of mammalian nucleoli essential for ribosome biogenesis.
- 1 cites
Add DNA and Nucleic Acid Chemistry as an interest in JClub
Browse JClub
Journals this month
- bioRxiv6131
- medRxiv1703
- PNAS447
- Sci Adv354
- JAMA262
- Environ Res230
- BMJ182
- Environ Pollution165
- Nat Commun161
- Science141
- Nature138
- Lancet128
- Cell Rep120
- NEJM119
- mBio107
- Plant Cell Environ107
- Curr Biol106
- J Exp Bot106
Topics moving, week to 23 Oct 2026
- Single-cell and spatial transcriptomics6
- Neuroinflammation and Neurodegeneration Mechanisms5
- Bacteriophages and microbial interactions5
- Gut microbiota and health5
- Genomics and Phylogenetic Studies4
- Cancer Genomics and Diagnostics4
- Cancer Immunotherapy and Biomarkers4
- Alzheimer's disease research and treatments3
- Inflammatory Bowel Disease3
- Influenza Virus Research Studies3