Antimicrobial Resistance in Staphylococcus

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Staphylococcus aureus wall teichoic acid structure dictates virulence potential and resistance to host defenses.
Science Advances · 23 Oct 2026 · Journal Article
SasF enzyme is essential for S. aureus resistance to skin fatty acids and is required for skin colonization and infection, highlighting its role in virulence.
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The staphylococcal type VII secretion system delays inflammatory cell death during macrophage infection
bioRxiv · 10 Oct 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.10.30.685513
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The Staphylococcus aureus carotenoid staphyloxanthin modifies the structure of phosphatidylglycerol lipid bilayers
bioRxiv · 6 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.06.25.732829
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SroA links SigS-dependent stress signaling to metabolic remodeling in Staphylococcus aureus
bioRxiv · 6 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.05.15.725384
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Positive control of the integrative and conjugative element Tn916 and its limited gene expression in transconjugants
bioRxiv · 2 Oct 2026 · Preprint
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Biotope-dependent resistance to reactive oxygen species, antibiotic tolerance, and virulence of Staphylococcus aureus.
Communications Biology · 1 Oct 2026 · Journal Article
Milk-grown Staphylococcus aureus exhibits extreme resistance to reactive oxygen species, antimicrobial tolerance, and accelerated killing in a larval infection model compared to serum-grown bacteria.
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The Management of Fulminant Clostridioides difficile Infection in an Immunocompromised Patient: Balancing Risk and Necessity.
Gastroenterology · 1 Oct 2026 · Journal Article
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Lacticaseibacillus rhamnosus GG enhances gefitinib efficacy and reduces treatment-related toxicity via propionyl-L-carnitine regulation.
Cell Reports · 1 Oct 2026 · Journal Article
Lacticaseibacillus rhamnosus GG enhances gefitinib efficacy and reduces gastrointestinal and hepatic toxicity without changing systemic drug levels in mice.
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Initial Vancomycin Taper May Reduce Early Recurrence of Clostridioides difficile Infection.
Gastroenterology · 1 Oct 2026 · Journal Article
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A novel rapid host cell entry pathway determines the intracellular fate of Staphylococcus aureus.
eLife · 23 Sept 2026 · Journal Article
A rapid sphingomyelin-dependent entry pathway in S. aureus alters intracellular fate, influencing bacterial replication and host cell death within minutes of contact.
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The iron paradox and particle size sensing: transcriptomic response of Enterococcus faecalis to non-nutritive minerals.
Applied and environmental microbiology · 23 Sept 2026 · Journal Article
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Transferable optrA-mediated linezolid resistance in enterococci from high-altitude river sediments of Gilgit-Baltistan, Pakistan.
Applied and environmental microbiology · 23 Sept 2026 · Journal Article
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Toward a digital twin for Enterococcus faecium: An experimentally validated manually curated genome-scale metabolic model of strain TX0016 reproduces high-throughput phenotyping data
bioRxiv · 22 Sept 2026 · Preprint
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TrbA binds and locks a sliding clamp KorB to repress transcription on multi-drug resistance plasmids.
Journal of bacteriology · 17 Sept 2026 · Journal Article
TrbA binds and locks KorB, a DNA-sliding clamp, to repress transcription on multi-drug resistance plasmids, revealing a conserved clamp-locking mechanism involving multiple partners.
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Distinctive Lacritin Cleavage-Potentiated Bactericidal Alteration of the P. aeruginosa Transcriptome
bioRxiv · 17 Sept 2026 · Preprint
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The host environment rather than biofilm growth activates stress responses and conveys ciprofloxacin tolerance in Staphylococcus aureus
bioRxiv · 17 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.08.07.669083
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Defining the order of assembly of the Clostridioides difficile divisome complex.
Journal of bacteriology · 17 Sept 2026 · Journal Article
C. difficile assembles a unique divisome complex in three phases, with PBP1 replacing FtsW-FtsI in septal peptidoglycan synthesis, highlighting a distinct bacterial division mechanism.
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Loss of the Ap(4)A hydrolase YqeK impairs stress adaptation and virulence gene expression in Staphylococcus aureus.
Journal of bacteriology · 17 Sept 2026 · Journal Article
Loss of YqeK in Staphylococcus aureus causes a 1,000-fold increase in Ap 4 N levels and impairs stress resistance and virulence gene expression.
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Polyunsaturated fatty acids: host-derived antimicrobials against glycolytic Staphylococcus aureus.
Journal of bacteriology · 17 Sept 2026 · Journal Article
Polyunsaturated fatty acids effectively kill glycolytic Staphylococcus aureus strains, including persisters and small colony variants, by inducing lipid peroxidation.
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In Staphylococcus aureus, MbcS is a refunctionalized acyl-CoA synthetase that confers a fitness advantage during intra-species competition.
Journal of bacteriology · 17 Sept 2026 · Journal Article
MbcS, a refunctionalized acyl-CoA synthetase in Staphylococcus aureus, provides a significant fitness advantage during intra-species competition under nutrient-limited conditions.
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No Point Beating Around the Bedpan: Lessons from a Major Intra-Hospital NDM-Producing Escherichia coli Carriage Outbreak : a Mixed-Methods Study.
medRxiv · 8 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.07.06.26354129
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Candida albicans reprograms Staphylococcus aureus glycolytic metabolism to drive enhanced virulence.
Virulence · 4 Sept 2026 · Journal Article
Candida albicans reprograms Staphylococcus aureus glycolytic pathways, increasing its virulence by 2- to 3-fold in glucose-rich environments.
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The Parkinson's disease-linked G2019S mutation of LRRK2 increases NADPH oxidase-2 activity in neutrophils for superior control of bacterial infections.
Cellular & molecular immunology · 1 Sept 2026 · Journal Article
The G2019S mutation in LRRK2 enhances NADPH oxidase-2 activity in neutrophils, improving bacterial infection control in mice by 2- to 3-fold.
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Cryptotanshinone inhibits Staphylococcus aureus NdhC via uncompetitive inhibition: Collateral sensitivity in respiratory-deficient SCVs.
Virulence · 30 Aug 2026 · Journal Article
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Metagenomic characterization of potential exposure to genetic hazards at the interface between grazing livestock and Przewalski's gazelle.
Environmental pollution · 28 Aug 2026 · Journal Article
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Immune silencing by a lipid virulence factor of Staphylococcus.
Communications Biology · 26 Aug 2026 · Journal Article
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