Autism Spectrum Disorder Research

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Longitudinal Receptive-Expressive Language Profiles in Young Autistic Children
medRxiv · 19 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.06.02.26354680
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Unique Amygdala Signatures and Shared Prefrontal Deficits in Autism: Mapping Social Heterogeneity via Naturalistic functional MRI
bioRxiv · 18 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.02.26.708280
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Reduced dorsal CA1 activity limits retention of the temporal component of declarative memory in the Cntnap2 knockout mouse model of autism.
eLife · 13 Oct 2026 · Journal Article
Reduced dorsal CA1 activity in Cntnap2 knockout mice impairs long-term retention of temporal associations in declarative memory.
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Human-specific CCG-repeat insertion in the RBFOX1 promoter implicated in autism and speech enhances EGR1-responsive activity
bioRxiv · 12 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.04.21.719679
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p70 ribosomal protein S6 Kinase (p70S6K) as a potential peripheral biomarker for autistic symptoms in 16p11.2 deletion and duplication syndromes
bioRxiv · 12 Oct 2026 · Preprint
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Retinal cell mosaics in the valproate-induced rat model of autism spectrum disorder
bioRxiv · 8 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.06.14.732149
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Behavioral phenotypes and neuronal biomarkers in F1 mutant macaque model of SHANK3-associated autism spectrum disorders.
Neuron · 7 Oct 2026 · Journal Article
Heterozygous SHANK3 +/- macaques exhibit sleep disturbances, social interaction changes, stereotypical behaviors, and altered brain connectivity, modeling autism spectrum disorder features.
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Neurocognitive characteristics of perceptual feedback processing differ in autism
bioRxiv · 6 Oct 2026 · Preprint
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https://jclub.com.au/a/10.1101/2024.07.23.604831
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Fecal extracellular vesicles from adults with autism spectrum disorder affect mouse behavior and gut motility by targeting the neuronal nitrergic pathway
bioRxiv · 2 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.28.754921
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Structural changes in autism reflect atypical brain network organization and phenotypical heterogeneity: a deep network approach
bioRxiv · 21 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.11.02.686152
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Infants at high and low likelihood for autism show different EEG developmental trajectories in speech tracking and statistical learning.
eLife · 21 Sept 2026 · Journal Article
Infants at high likelihood for autism show reduced neural speech tracking and altered statistical learning trajectories, with significant implications for early diagnosis.
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https://jclub.com.au/a/42766422
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Sensory and developmental phenotyping of C. elegans parses autism associated genes into behavioural classifications
bioRxiv · 21 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.03.27.714775
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Convergent and divergent phenotypic impacts of estradiol on neurodevelopmental disorder risk genes
bioRxiv · 19 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.02.18.706588
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Feasibility of multimodal behavioral, gaze, and EEG measurement of natural scene segmentation in autism
bioRxiv · 17 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2025.12.17.695033
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Transcriptome-based classification in mice with ASD-risk mutations.
Science · 17 Sept 2026 · Journal Article
Transcriptome analysis of 17 ASD-risk mouse lines reveals two opposing molecular states with distinct sex, regional, and developmental features.
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https://jclub.com.au/a/42752124
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Clinical outcomes with chronic adaptive versus conventional DBS in Parkinson's disease: A pilot randomized crossover trial
medRxiv · 11 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.09.07.25335282
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Developmental Dynamics of Phenotypic Architecture in ASD
bioRxiv · 9 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.05.25.727621
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Mid-to-late pregnancy: A critical window for the protective effect of green space against autism spectrum disorder (ASD).
Environmental pollution · 8 Sept 2026 · Journal Article
Green space exposure during mid-to-late pregnancy (6 to 1 month before birth) is linked to significantly lower odds of ASD in children, independent of PM2.5 levels.
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Autistic children show reduced activity in left superior temporal cortex in response to social-emotional meaning in language
bioRxiv · 6 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.01.02.697285
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Complex genotype-phenotype relationships in neurodevelopmental disorders.
Trends in Genetics · 1 Sept 2026 · Review
Genotype-phenotype relationships in neurodevelopmental disorders are highly complex, with diverse clinical outcomes observed even among individuals with the same risk gene variants.
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https://jclub.com.au/a/41986224
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Design of optimized epigenetic regulators for durable gene silencing with application to PCSK9 in nonhuman primates.
Nature Biotechnology · 1 Sept 2026 · Journal Article
Optimized TALE-based epigenetic regulators achieve 98% gene silencing with durable effects over 343 days in primates.
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https://jclub.com.au/a/41034497
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EEG functional connectivity as a prognostic biomarker of adaptive function in autistic people
medRxiv · 28 Aug 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.05.17.25327836
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Maternal-fetal immune conflict contributes to male-specific impairments in a mouse model of neurodevelopmental disorders
bioRxiv · 27 Aug 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.02.02.703351
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Assigning Targetable Pathways to Transdiagnostic Subgroups Across Neurodevelopmental Disorders
bioRxiv · 26 Aug 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.03.04.641443
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