D2C7-ATC therapy is linked to prolonged survival in a subset of patients with IDHwt recurrent glioblastoma, with a median overall survival of 17.38 months in certain cases.
Toxin Mechanisms and Immunotoxins
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A human cell-free translation screen identified NT-2 as a ribosomal inhibitor binding the peptidyl transferase center, revealing its role as an environmental toxin in mammalian protein synthesis.
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Lipid nanoparticle delivery of mRNA achieves 100% higher T cell viability and enhanced protein expression compared to electroporation in serial human T cell engineering.
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