Liver Diseases and Immunity
Moving in Journal of hepatology, Gastroenterology, Gut, Nature reviews. Gastroenterology & hepatology, bioRxiv, Cell Metabolism, Cell Reports and Nature Medicine.
- Moved, week to 23 Oct 2026
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Latest in Liver Diseases and Immunity
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Genetic variants in ABCB4, ABCB11, and ATP8B1 are linked to a spectrum of adult and paediatric cholestatic liver diseases, including PFIC types 1-3.
Hepatic glutamine depletion is linked with increased CD4+ T cell inflammation and worsened liver damage in MASLD patients and mouse models.
- Open access
B cells with gut-homing markers and proinflammatory functions are increased at the asymptomatic stage in mice and patients susceptible to ICI-colitis.
- Open access
A HER2-targeted quadruplet regimen achieved a 55% objective response rate in first-line treatment of HER2-positive unresectable biliary tract cancer, showing promising efficacy.
- Open access
Over 50% of strictly defined immune tolerant chronic hepatitis B patients transition to immune active disease within five years, especially those with high-normal ALT levels.
- Open access
Family history of colorectal cancer increases CRC incidence similarly in IBD patients and the general population, especially with multiple affected relatives, but the relative impact is weaker in IBD.
- Open access
Clonal lymphocyte expansions with JAK-STAT mutations drive gluten-free diet resistance in type 2 refractory celiac disease, revealing a pathogenic continuum.
- Open access
Gastrointestinal involvement affects up to 90% of systemic sclerosis patients, causing diverse symptoms from esophageal dysphagia to colonic dilation.
- Open access
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Topics moving, week to 23 Oct 2026
- Single-cell and spatial transcriptomics6
- Neuroinflammation and Neurodegeneration Mechanisms5
- Bacteriophages and microbial interactions5
- Gut microbiota and health5
- Genomics and Phylogenetic Studies4
- Cancer Genomics and Diagnostics4
- Cancer Immunotherapy and Biomarkers4
- Alzheimer's disease research and treatments3
- Inflammatory Bowel Disease3
- Influenza Virus Research Studies3