SMURF1 and SMURF2 ubiquitinate CDK9, regulating SMAD2-driven transcription during mesendoderm differentiation in embryonic development.
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SMURF1 and SMURF2 ubiquitinate CDK9, regulating SMAD2-driven transcription during mesendoderm differentiation in embryonic development.
TGF-β-PDL1 signaling in neutrophils maintains lung barrier integrity during hyperinflammation by regulating neutrophil behavior in murine models.
Reg-EXTL3 axis promotes nerve-cancer interactions in pancreatic ductal adenocarcinoma, with silencing reducing tumor progression and pain in mice.
TIF1γ is essential for maintaining regulatory T cell stability by restraining β-catenin signaling, preventing inflammatory reprogramming during immune challenges.
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