Adipose Tissue and Metabolism

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The hepatic mitochondrial landscape
bioRxiv · 22 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.07.03.736316
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Author Correction: Exercise-induced anti-obesity effects in male mice generated by a FOXO1-KLF10 reinforcing loop promoting adipose lipolysis.
Nature Communications · 21 Oct 2026 · Published Erratum
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Alternative organelle targeting of OPA1 mediates fatty acid release from lipid droplets
bioRxiv · 18 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.05.07.723579
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Voluntary Exercise Differentially Affects High-Fat Induced Metabolic Phenotypes Across BXD Mouse Strains
bioRxiv · 2 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.28.752290
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Rethinking mitochondrial metabolism: Intraindividual variability meets population constraints.
Trends in Genetics · 1 Oct 2026 · Review
Mitochondrial DNA acts as a primary evolutionary engine driving nuclear coadaptation, expanding mitonuclear haplotype pools within species.
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Muscle Fiber- and Cell Type-Specificity of Training Adaptation in Male Mice
bioRxiv · 30 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.11.04.686534
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Aged white adipose tissue is rejuvenated in a young host through thermogenic remodeling of mature adipocytes
bioRxiv · 30 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2025.12.28.696721
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Multi-Omic, Multi-Tissue Responses to Acute Exercise in Sedentary Adults: Findings from the Molecular Transducers of Physical Activity Consortium
bioRxiv · 30 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.02.27.702183
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Angiotensin II and cAMP signaling pathways regulate mitochondrial biogenesis and activity in human adrenocortical cells.
bioRxiv · 25 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.05.06.723032
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Single-cell analyses reveal tissue-specific contextualization 1 of HIF-1 activity
bioRxiv · 22 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2024.07.02.601765
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Disrupted glucocorticoid rhythms selectively induce severe skeletal muscle insulin resistance and uncouple obesity from hepatic steatosis.
Cell Reports · 22 Sept 2026 · Journal Article
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Androgen-PDH axis modulates sexual dimorphism of mitochondrial respiration in visceral fat.
Cell Reports · 22 Sept 2026 · Journal Article
Androgen-AR signaling suppresses mitochondrial respiration in visceral fat by downregulating Pdhb, contributing to sex differences in fat accumulation and metabolic risk.
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Transient activation of ciliary CCR2 signaling promotes the initiation of adipogenesis.
Nature Communications · 17 Sept 2026 · Journal Article
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ENPP1 buffers extracellular cGAMP in brown adipose tissue to limit insulin resistance.
Cell Reports · 15 Sept 2026 · Journal Article
ENPP1 prevents extracellular cGAMP accumulation in brown adipose tissue, reducing insulin resistance and obesity in high-fat diet conditions.
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https://jclub.com.au/a/42743059
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Abnormal glucose metabolism and muscle mass decline by bisphenol A or bisphenol S in skeletal muscle of male mice:inhibition of mitophagy by downregulation of the ERα/AMPK/ULK1 pathway.
Environmental research · 15 Sept 2026 · Journal Article
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The hypoxic response extends lifespan through a bioaminergic and peptidergic neural circuit.
bioRxiv · 11 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.05.04.652087
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Functional primary human 3D skeletal muscle models enable exercise and metabolic research
bioRxiv · 9 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.06.29.735246
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Mitochondrial fission factor regulates mitochondrial Ca(2+) homeostasis and neuronal activity in AgRP neurons.
Neuron · 2 Sept 2026 · Journal Article
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Mitochondrial calcium influx-driven bioenergetics selectively enable drug addiction.
Nature Neuroscience · 2 Sept 2026 · Journal Article
Mitochondrial calcium influx via MCU in dopaminergic neurons drives drug-specific dopamine release, enabling addiction behaviors without affecting natural rewards.
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Sex- and fiber type-specific remodeling of the muscle proteome implicates CSRP3 in resistance training-induced hypertrophy.
Nature Communications · 2 Sept 2026 · Journal Article
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https://jclub.com.au/a/42823422
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The senescence-stiffening loop: Extracellular matrix remodeling, hypoperfusion, and mitochondrial dysfunction drive tissue aging.
Cell Metabolism · 1 Sept 2026 · Review
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Competitive catabolism drives hyperglycemia and hyperinsulinemia in obesity.
Cell Metabolism · 1 Sept 2026 · Journal Article
Competitive catabolism of fatty acids and glucose in obesity causes hyperglycemia and hyperinsulinemia, driven by a physiological circuit identified through modeling.
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Brown fat protects against hepatic oxidative stress by remodeling the circulating metabolome.
Cell Metabolism · 1 Sept 2026 · Journal Article
Brown adipose tissue reduces hepatic oxidative stress by releasing 3-hydroxystearic acid, a cold-induced metabolite that modulates liver mitochondrial function.
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Acetyl-CoA carboxylase carboxyltransferase β subunit enhances NaHCO(3) tolerance and fat content.
Plant Physiology and Biochemistry · 1 Sept 2026 · Journal Article
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Transcriptional response to warm temperatures is confounded by organ-specificity
bioRxiv · 31 Aug 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.08.05.668523
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