Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

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Papers in 60 days: 11

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Type I IFN promotes ILC2-to-ILC1 plasticity in pre-clinical radiation-induced lung injury.
Nature Communications · 20 Oct 2026 · Journal Article
Type I interferon promotes ILC2-to-ILC1 plasticity, contributing to radiation-induced lung injury in a mouse model.
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Baseline predictors of mortality in non-idiopathic pulmonary fibrosis interstitial lung disease - A retrospective cohort study at a tertiary centre in Malaysia
medRxiv · 19 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.02.12.26346139
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GM-CSF Programs Alveolar Macrophages to Maintain Pulmonary Lymphocyte Homeostasis
bioRxiv · 2 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.28.753165
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Lineage identity governs oncogene dependence in mouse NSCLC models of KRAS inhibitor resistance.
Nature Genetics · 1 Oct 2026 · Journal Article
Lineage transformation to squamous identity confers KRAS inhibitor resistance in mouse lung adenocarcinoma models.
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Probability of causation in individual workers: Lung cancer due to occupational exposure to asbestos
medRxiv · 30 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.02.06.26345596
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Single cell transcriptomics in a treatment-segregated cohort exposes a STAT3-regulated therapeutic gap in idiopathic pulmonary fibrosis
bioRxiv · 17 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.06.16.659944
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HBsAg decline and clearance with peg-IFN therapy added to nucleos(t)ide analogues: an individual participant data meta-analysis of prospective trials (PROSPER).
Gut · 7 Sept 2026 · Meta-Analysis
Adding peg-IFN to nucleos(t)ide analogue therapy achieves HBsAg loss in up to 38% of chronic hepatitis B patients with low initial HBsAg levels.
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Integration of proteomic aging clocks in a phase 2a clinical trial supports simultaneous geroprotective assessment.
Nature Biotechnology · 7 Sept 2026 · Journal Article
Six proteomic aging clocks consistently predicted lower biological age in a 12-week clinical trial of rentosertib for idiopathic pulmonary fibrosis.
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Mechanisms of acquired resistance to osimertinib in EGFR T790M-Positive lung adenocarcinoma.
Frontiers in Genetics · 4 Sept 2026 · Journal Article
Heterogeneous resistance mechanisms, including EGFR mutations, bypass signaling, and transformation, emerge in EGFR T790M-positive lung adenocarcinoma after 14.2 months of osimertinib treatment.
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MAPK13 controls structural remodeling and disease after epithelial injury
bioRxiv · 28 Aug 2026 · Preprint
MAPK13 regulates epithelial stem cell-driven remodeling and disease, with knockout mice showing protection against hyperplasia and immune activation after injury.
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https://jclub.com.au/a/10.1101/2024.05.31.596863
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Chronic TGFB1 Signaling Drives Aberrant Alveolar-Basaloid Metaplasia through a KRT17-Stratifin migratory complex
bioRxiv · 28 Aug 2026 · Preprint
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