HEP-50768, a potent and selective inverse agonist of MRGPRX4, suppresses bile-acid-induced pruritic behaviors in humanized rats, indicating its potential for cholestatic itch treatment.
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Dermatology and Skin Diseases
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Restoring IL-17D in glioblastoma reprograms CD93(+) antigen-presenting cells, extending survival by activating immune responses in mouse models.
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Topics moving, week to 23 Oct 2026
- Single-cell and spatial transcriptomics6
- Neuroinflammation and Neurodegeneration Mechanisms5
- Bacteriophages and microbial interactions5
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- Cancer Immunotherapy and Biomarkers4
- Alzheimer's disease research and treatments3
- Inflammatory Bowel Disease3
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