Esophageal Cancer Research and Treatment

Moving in Gastroenterology, Gut, Nature Medicine, JAMA, medRxiv, Nature Reviews Cancer, Nature reviews. Gastroenterology & hepatology and The American Journal of Human Genetics.

Moved, week to 23 Oct 2026: 0
Papers in 60 days: 11

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The urgent challenge of gastroesophageal cancer.
Nature Reviews Cancer · 9 Oct 2026 · Journal Article
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Perioperative immunotherapy for resectable gastric and gastro-oesophageal junction adenocarcinoma: overall survival results.
Nature reviews. Gastroenterology & hepatology · 5 Oct 2026 · Journal Article
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Non-Endoscopic Screening for Barretts Esophagus Using a DNA Methylation-Based Assay: Real-World Experience in 11,991 Patients
medRxiv · 2 Oct 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.11.20.25340693
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Long-Term Follow-Up From the Barrett's Esophagus Screening Trial 3 Demonstrates High Negative Predictive Value of Capsule Sponge-Trefoil Factor 3 Test for Esophageal Adenocarcinoma.
Gastroenterology · 1 Oct 2026 · Journal Article
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Large-scale esophageal cancer screening through noncontrast computed tomography and artificial intelligence.
Nature Medicine · 1 Oct 2026 · Multicenter Study
EAGLE AI model detects early esophageal cancer with 90% sensitivity and 98.5% specificity from chest CT scans across multiple centers, enabling scalable screening.
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Liquid biopsy for early detection of pancreatic ductal adenocarcinoma.
Nature Medicine · 1 Oct 2026 · Multicenter Study
A blood-based microRNA assay combined with carbohydrate antigen 19-9 detects early-stage pancreatic ductal adenocarcinoma with 86.8% sensitivity in a large international study.
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Genomic Analyses Reveal Mutational Signatures and Frequently Altered Genes in Esophageal Squamous Cell Carcinoma.
The American Journal of Human Genetics · 23 Sept 2026 · Expression of Concern
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Coordinated cellular programmes distinguish responses to neoadjuvant PD-L1 blockade and potentiate combinatorial immunotherapy in ESCC.
Gut · 18 Sept 2026 · Journal Article
Coordinated cellular programmes involving exhausted T cells, regulatory T cells, memory B cells, and macrophages predict responses to neoadjuvant PD-L1 blockade in ESCC.
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Response to: 'Rectal versus colonic submucosal cancer rates and procedural outcomes in large non-pedunculated polyps: French ESD registry data' by Van der Voort et al.
Gut · 7 Sept 2026 · Letter
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Achalasia and Risk of Esophageal Squamous Cell Carcinoma and Adenocarcinoma in a Multinational Study.
Gastroenterology · 1 Sept 2026 · Multicenter Study
Achalasia is strongly linked to esophageal squamous cell carcinoma, with an odds ratio of 9.46, but its connection to adenocarcinoma is weaker and largely explained by GERD.
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Surgical and Endoscopic Therapies for GERD.
JAMA · 1 Sept 2026 · Journal Article
Surgical and endoscopic therapies, including radiofrequency, plication, and mucosal resection, offer diverse options for treating GERD patients.
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