Neurotransmitter Receptor Influence on Behavior
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Individual dopaminergic neurons in Drosophila larva can induce diverse functions, including memory formation and locomotion modulation, with each neuron exhibiting a unique yet overlapping effect set.
- Open access
LSD occupies 5-HT2AR with high affinity and increases global cerebral blood flow and internal carotid artery flow in humans.
Blocking cholinergic interneurons in the nucleus accumbens prevents morphine-conditioned place preference without affecting dopamine increases in mice.
A circuit from the amygdala to the anterior hypothalamic nucleus (AHN) heightens stress sensitivity, with increased negative valence processing in previously stressed mice.
- Open access
Reduced serotonin neuron activity in the dorsal raphe during pregnancy drives food-craving-like behavior in mice, with SK3 ion channels playing a key role.
Selective activation of 5-HT(2A) receptors over 5-HT(2B) receptors was achieved with derivatives showing high specificity, confirmed by cryo-EM structures.
- Open access
Cerebellar input streams encode dopamine rewards with both predictive and instructive signals, influencing motivated behavior in mice.
Locus coeruleus noradrenaline neurons exhibit topographic organization linked to distinct brain regions and functions in mice.
- Open access
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