Tuberculosis Research and Epidemiology
Moving in Journal of bacteriology, mBio and mSystems.
- Moved, week to 22 Oct 2026
- 3
- Papers in 60 days
- 30
Rebuilt
Moved this week
CysK2-mediated cysteine biosynthesis is essential for copper resistance in Mycobacterium tuberculosis, with a single amino acid substitution in H37Rv impairing this function.
- 1 cites
Latest in Tuberculosis Research and Epidemiology
Newest first · last 60 days
Cryo-EM structures reveal how WzmWzt transporter binds and translocates mycobacterial lipid-linked galactan in M. tuberculosis, highlighting key conformational changes.
- Open access
Integrating protein structural context enables 96.5% accurate prediction of resistance-conferring mutations in M. tuberculosis proteins.
- Open access
Human CD1c-autoreactive T-cells exhibit cytotoxic responses and reduce Mtb burden in infected antigen-presenting cells, with 50% showing enhanced activation during infection.
- Open access
Semapimod inhibits L-leucine uptake in Mycobacterium tuberculosis, reducing bacterial load in infected mice despite no in vitro efficacy.
- Open access
Gene conversion drives over 300 diversity hotspots in M. tuberculosis, especially within virulence and antigen-related gene families, increasing genetic variation by more than tenfold.
- Open access
Tobramycin increases Mycobacterium abscessus survival by inducing whiB7, promoting persistent infection in cystic fibrosis airway conditions.
- Open access
Migration increases the genetic diversity of Mycobacterium tuberculosis complex strains in Hamburg but does not change local transmission patterns, which remain lineage-specific.
- Open access
Strong, sustained type I IFN signaling intrinsically impairs IFNγ responses in macrophages, increasing susceptibility to tuberculosis in Mycobacterium tuberculosis infection.
- Open access
Multiple local PfDHFR I164L haplotypes have expanded in Uganda, increasing pyrimethamine resistance from 19.4% to 32.4% between 2016 and 2022.
- Open access
Deletion of rv3400 in Mycobacterium tuberculosis causes a 30-fold increase in β-D-glucose-1-phosphate and impairs trehalose-based growth, highlighting its essential role in metabolism.
- Open access
Cryo-EM structures reveal how the M. tuberculosis DprE1-DprE2 complex interacts with anti-tubercular drugs, providing insights into their mechanisms of inhibition.
Co-occurrence of drug resistance variants in Plasmodium falciparum across Ethiopia's diverse transmission settings highlights emerging threats to malaria control.
- Open access
Machine learning identifies key chemical features, including nitrogen-containing aromatic scaffolds, that enhance mycobacterial outer membrane permeation, improving antibiotic potential.
- Open access
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Journals this month
- bioRxiv6244
- medRxiv1789
- PNAS447
- Sci Adv354
- JAMA268
- Environ Res246
- BMJ196
- Nat Commun173
- Environ Pollution167
- Nature151
- Applied & Environ Microbio145
- Science141
- Lancet128
- Cell Rep127
- NEJM119
- Plant Cell Environ118
- J Exp Bot107
- mBio107
Topics moving, week to 22 Oct 2026
- Single-cell and spatial transcriptomics6
- Neuroinflammation and Neurodegeneration Mechanisms5
- Cancer Immunotherapy and Biomarkers5
- Gut microbiota and health5
- Cancer Genomics and Diagnostics4
- Bacteriophages and microbial interactions4
- CAR-T cell therapy research3
- Lung Cancer Treatments and Mutations3
- Liver Disease Diagnosis and Treatment3
- Dementia and Cognitive Impairment Research3