A curated genome-scale nucleotide diversity panel of non-human primates.

A curated genome-scale nucleotide diversity panel of 3,240 non-human primates from 269 species and 71 genera was created using a ploidy-aware variant calling approach.

• Why it matters: This resource addresses limitations in existing primate genomic datasets caused by data processing discrepancies, especially in sex-linked regions, and aims to enhance comparative analyses.
• What they did: The authors combined publicly available short-read sequencing data, recent primate genome assemblies, and a ploidy-aware variant calling method to generate the diversity panel and a multiple-genome alignment for cross-species comparison.
• The result: This curated primate diversity resource provides a foundation for future studies in primate evolution, speciation, and sex chromosome evolution, enabling more accurate and comprehensive comparative research.