The future of marsupial gene editing: What's in the (tool) pouch?

Marsupial genome editing has only been achieved in Monodelphis domestica, despite the availability of high-quality genomes for other species.

• Why it matters: Advancing genome editing in marsupials is crucial for improving research models and addressing ecological challenges faced by these unique mammals.
• What they did: The review discusses marsupial-specific challenges and opportunities in zygote-based and germ cell transplantation approaches, summarizing current efforts to expand genome editing tools.
• The result: Filling this gap could enhance marsupial research and conservation, enabling more effective use of genome editing for scientific and ecological applications.