A transcriptional switch from KLF activators to repressors during early postnatal development regulates neuronal maturation in the mouse neocortex.
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Kruppel-like factors research
Moving in Cancer Research, eLife, Nature Communications and Nature reviews. Gastroenterology & hepatology.
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KLF4 drives a KRT13+ hillock-like cell state in lung squamous cell carcinoma, linked to therapy resistance and tumor heterogeneity.
GZF1 and ZFP57 reciprocally bind to safeguard Dlk1-Dio3 imprinting, preventing methylation changes that threaten parent-specific gene expression during development.
- Open access
Long non-coding RNAs regulate the colorectal cancer microenvironment, influencing tumor progression and resistance, with potential as biomarkers and therapeutic targets.
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