The structure of PCDH1 bound to Andes virus spike reveals how the virus recognizes host cells, with PCDH1 engaging a deep pocket in the spike's Gn protomers.
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The structure of PCDH1 bound to Andes virus spike reveals how the virus recognizes host cells, with PCDH1 engaging a deep pocket in the spike's Gn protomers.
AKAV reprograms host mRNA granules and translation machinery to enhance its cap-snatching efficiency, with PKR-eIF2α signaling playing a central role.
Filovirus reactive antibodies in Guinea's wildlife hunting communities indicate ongoing zoonotic spillover events involving multiple viruses, with 4.9% of individuals showing IgG binding.
SNX17 is essential for efficient Rift Valley fever virus infection, with its removal causing a substantial reduction in infection rates in knockout cells.
A single residue, Arg577 in Gc protein, determines SFTSV's neutralization sensitivity, replication fitness, and virulence in different strains.
Global dengue virus lineages show regional differences in diversity, with five cosmopolitan lineages detected in at least seven of nine regions.
Andes virus (ANDV) is the only orthohantavirus known to transmit between humans, posing unique challenges for disease control and management.
Outbreak risks for zoonotic and vector-borne diseases are highest in mosaic landscapes with human, livestock, and forest coexistence, influenced by ecosystem and climate factors.
Tick-borne viruses pose an increasing global threat, with over 100 identified viruses affecting humans and animals, driven by ecological and climate factors.
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