Syntaxin11 deficiency inhibits CRAC channel priming, reducing calcium entry and gene expression in T lymphocytes independently of membrane trafficking, with implications for immune disorders.
- Open access
Ion Channels and Receptors
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Loss of C. elegans GRK-1 reduces isothermal tracking duration by affecting neuronal states in RIM and AVA interneurons.
- Open access
Starvation causes a near-complete suppression of heat-evoked reversals in Caenorhabditis elegans by altering AWC neuron responses and neuropeptide signaling.
- Open access
Elevated plasma oleic acid in hypertriglyceridaemia-associated acute pancreatitis is linked to increased acute lung injury severity via the PIEZO1/NR4A1/CPT1A pathway.
- 3 cites
CaZAT11 positively regulates cold tolerance in pepper and interacts with CaSTOP1 in the nucleus.
- Open access
Mutations in the intracellular subdomain of LRRC8A cause constitutive activation of VRAC channels, highlighting its role as a key regulatory hub.
- Open access
- 1 cites
LRRC8A/D heteromeric channels are activated by cell swelling and modulated by sybodies, with a specific structure of four A and two D subunits revealing key conformational states.
- Open access
PRRT2 enhances Nav channel slow inactivation and delays recovery, affecting neuronal excitability from zebrafish to humans.
- Open access
Lamprey KCNE0, an early-diverging KCNE family member, induces constitutive KCNQ1 activity, highlighting its unique role in vertebrate ion channel regulation.
- Open access
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