Diversity in nutrient sensing by Candida auris is linked to its ability to evade immune responses across different host environments.
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Diversity in nutrient sensing by Candida auris is linked to its ability to evade immune responses across different host environments.
Olorofim achieved clinical success in over 73% of patients with disseminated coccidioidomycosis, including those with severe CNS involvement, in a phase 2b trial.
PinA and XYP1 peptides demonstrate strong, stable binding to Candida albicans membranes, effectively inhibiting fungal growth in vitro without harming human cells.
IL-1 family signalling is essential for mucosal defence against systemic Candida albicans infection, with its loss leading to dissemination and mortality in neutropenic conditions.
Forty-five percent of Ecuadorian field biologists show prior exposure to Histoplasma capsulatum, revealing significant occupational risk in endemic environments.
Advances in molecular techniques and point-of-care tests promise faster, more accurate diagnosis of invasive fungal infections, potentially saving lives and reducing resistance.
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