Host receptors that recognize Candida albicans epitopes are classified into direct and co-receptor categories, with key receptors including Dectin-1/2/3, Mincle, MR, and TLR2/4.
Medical Mycology
Oxford University Press · Microbiology & Mycology · ISSN 1369-3786, 1460-2709
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Genomic analysis reveals diverse Clade I Candidozyma auris isolates with healthcare-associated clusters and antifungal resistance in Malaysia.
Multiplex qPCR assay detects histoplasmosis and pneumocystosis with 100% and 80% sensitivity respectively in PLWHA, but shows limited sensitivity for TB and cryptococcosis.
Heteroresistance to fluconazole, defined by HFL/MIC ≥8, was present in 61.4% of Cryptococcus isolates but was not significantly linked to six-month relapse in patients with neurocryptococcosis.
Posttransplant Candida colonization and surgical complications are identified as key risk factors for invasive candidiasis in solid organ transplant recipients within the first year.
An outbreak of mucormycosis caused by Rhizomucor pusillus occurred in a Brazilian HSCT unit, with four cases identified over ten months and three patients surviving.
Outbreaks of rare and emerging molds in hospitals are linked to high mortality, requiring systematic investigation and strengthened surveillance systems.
28-day mortality in Candida auris candidemia patients was 41.1%, with higher Charlson Comorbidity Index and SOFA scores independently linked to death.
Poor glycemic control in diabetic patients is linked to an 83.3% prevalence of Candida infections, while good control is associated with 64.1% dermatophyte infections.
Advances in molecular techniques and point-of-care tests promise faster, more accurate diagnosis of invasive fungal infections, potentially saving lives and reducing resistance.
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Seroprevalence of anti-Coccidioides IgG antibodies is 7.3% among residents in nine municipalities of Sonora, Mexico, indicating widespread exposure to Coccidioides spp. in an endemic region.
Forty-five percent of Ecuadorian field biologists show prior exposure to Histoplasma capsulatum, revealing significant occupational risk in endemic environments.
Entomophthoromycosis exhibits distinct epidemiological patterns, clinical forms, and a 10.93% overall mortality rate across 405 global cases from 2000 to 2023.
Posaconazole and surgery effectively manage Alternaria spp. infections in immunocompromised adults, with 52% of patients receiving oral therapy and 52% undergoing surgery.
Whole-genome sequencing reveals that four Trichophyton mentagrophytes genotype VII isolates from the UK form a highly clonal population distinct from other dermatophyte genotypes.
Severe COVID-19 patients in Brazil harbor diverse Aspergillus species with 100% showing non-wild-type phenotypes against posaconazole, indicating emerging antifungal resistance.
Urinary Histoplasma antigen detection identified 23.1% of symptomatic PLWH with suspected disseminated histoplasmosis, with high agreement between EIA and LFA methods.
Dematiaceous fungal keratitis accounts for 3.88% of fungal keratitis cases in North India, with Curvularia spp. being the most prevalent causative agent.
Anti-Aspergillus spp. IgG antibodies seroconvert in 70% of COVID-19-associated pulmonary aspergillosis patients, typically around 8 days after diagnosis in ICU settings.
Persistent candidemia occurs in 1 out of 3 cases and is linked to higher mortality and longer hospital stays in hospitalized patients.
Oral wash PCR detects Pneumocystis jirovecii pneumonia with 97.2% specificity but only 61.5% sensitivity in non-HIV immunocompromised patients.
Elevated terbinafine and fluconazole MICs in Trichophyton mentagrophytes complex isolates are linked to specific molecular changes, including SQLE mutations and increased MDR2 expression.
T. indotineae and T. mentagrophytes ITS genotype VII together account for 39.1% of T. mentagrophytes complex isolates in France, highlighting emerging public health concerns.
Non-albicans Candida species, especially C. parapsilosis and C. tropicalis, exhibit higher virulence factors and antifungal resistance, correlating with increased mortality in bloodstream infections.
Candida bloodstream infection occurs in approximately 3% of LVAD patients and results in a 62.5% mortality rate, highlighting its severity in this population.
A novel G982E mutation in MRR1 causes high-level fluconazole resistance and treatment failure in Candida parapsilosis.
Molecular identification revealed 90.4% of Microsporum canis complex isolates in Abu Dhabi, with 9.6% misidentified phenotypically, highlighting the importance of ITS sequencing.
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Topics moving, week to 23 Oct 2026
- Single-cell and spatial transcriptomics6
- Neuroinflammation and Neurodegeneration Mechanisms5
- Bacteriophages and microbial interactions5
- Gut microbiota and health5
- Genomics and Phylogenetic Studies4
- Cancer Genomics and Diagnostics4
- Cancer Immunotherapy and Biomarkers4
- Alzheimer's disease research and treatments3
- Inflammatory Bowel Disease3
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