Neurological disorders and treatments

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PD-RISK Index: Piloting an unsupervised toolkit to identify adults with Parkinson disease
medRxiv · 19 Oct 2026 · Preprint
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Sustained activation in basal ganglia and cerebellum after repetitive movement in cervical dystonia
bioRxiv · 19 Oct 2026 · Preprint
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https://jclub.com.au/a/10.1101/2023.03.19.533030
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Dorsal striatal astrocytes link dopamine to slow behavioral dynamics
bioRxiv · 14 Oct 2026 · Preprint
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https://jclub.com.au/a/10.1101/2024.12.01.626240
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WALK for Freezing of Gait in Parkinson's Disease: A Sham-Controlled Home Rehabilitation Trial
medRxiv · 10 Oct 2026 · Preprint
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Mechanical feasibility of retrograde trans-aqueduct access to the third ventricle: a human cadaveric and MRI morphometric study.
medRxiv · 7 Oct 2026 · Preprint
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Hindmarsh-Rose neuronal network with spike-timing-dependent plasticity demonstrates coordinated reset neuromodulation for Parkinson's disease
bioRxiv · 6 Oct 2026 · Preprint
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Heterogeneity in deep brain stimulation induced gamma oscillations explained by bifurcations in neural dynamics
medRxiv · 5 Oct 2026 · Preprint
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Electroencephalography for Radiation-Free Orientation Estimation of Directional Deep Brain Stimulation Leads
bioRxiv · 2 Oct 2026 · Preprint
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https://jclub.com.au/a/10.1101/2024.02.27.582287
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Brain stimulation boosts CSF flow.
Nature Neuroscience · 1 Oct 2026 · Journal Article
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Neuromodulation for restoring and amplifying brain function.
Nature Neuroscience · 1 Oct 2026 · Review
Neuromodulation's compensatory amplification (CA) can enhance brain function by strengthening repurposed processes, with four key factors enabling its effectiveness.
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Noninvasive decoding of typed sentences from human brain activity.
Nature Neuroscience · 1 Oct 2026 · Journal Article
Brain2Qwerty achieves a 29% character error rate in decoding sentences from magnetoencephalography in healthy volunteers, outperforming electroencephalography's 65%.
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Ethical considerations for implantable human brain-computer interfaces.
Nature Neuroscience · 1 Oct 2026 · Journal Article
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Common Electrophysiology Biomarkers Collected at Home Robustly Track Depression Recovery With Deep Brain Stimulation
medRxiv · 1 Oct 2026 · Preprint
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In conversation with Edward Chang.
Nature Neuroscience · 1 Oct 2026 · Interview
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Validity Gates Expose Limits of Longitudinal Multimodal Parkinson Disease Prediction
medRxiv · 25 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.23.26363849
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Challenging selective vulnerability in Parkinson's disease: a systematic review and meta-analysis
bioRxiv · 19 Sept 2026 · Preprint
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Choice-selective sequences dominate in cortical relative to thalamic inputs to NAc to support reinforcement learning.
Cell Reports · 17 Sept 2026 · Published Erratum
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On the feasibility of temporal interference stimulation of human brains using two arrays of electrodes
bioRxiv · 17 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.03.31.715653
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Phosphoproteome modifications and cortical circuit dysfunction are linked to the early-stage progression of alpha-synuclein aggregation.
bioRxiv · 17 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.01.24.634820
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An Implantable Wireless Battery-Free Spatially Selective Vagus Nerve Stimulator
bioRxiv · 15 Sept 2026 · Preprint
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Loss of interruption in the HTT CAG repeat is associated with somatic expansion and loss of medium spiny neurons in Huntington's disease.
Neuron · 14 Sept 2026 · Journal Article
Loss of interruption in the HTT CAG repeat correlates with increased somatic expansions and significant loss of medium spiny neurons in Huntington's disease.
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A precise atlas of the human subcortex
bioRxiv · 14 Sept 2026 · Preprint
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Midline Thalamic Neurons Show Early Hypersynchrony During Absence Seizures in Mouse Models
bioRxiv · 14 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2025.12.19.695246
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Clinical outcomes with chronic adaptive versus conventional DBS in Parkinson's disease: A pilot randomized crossover trial
medRxiv · 11 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.09.07.25335282
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The modern utility of awake deep brain stimulation surgery
medRxiv · 9 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.09.25.25336654
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Impaired cerebrovascular-cerebrospinal fluid coupling is associated with non-motor features of Lewy body disease
medRxiv · 9 Sept 2026 · Preprint
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A Comparative Evaluation of Structural MRI Foundation Models for Age, Sex, and Body-Mass Index Predictions
bioRxiv · 4 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.05.15.725427
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Coupled beta and high-frequency oscillations emerge from synchronized bursting in a minimal model of the parkinsonian subthalamic nucleus
bioRxiv · 3 Sept 2026 · Preprint
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Dermal Phospho-Alpha-Synuclein Among Individuals With and Without Cerebrospinal Fluid Aggregated Alpha-Synuclein
medRxiv · 2 Sept 2026 · Preprint
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Altered Striatal Acetylcholine Dynamics in a Model of Parkinson Disease and L-DOPA-induced Dyskinesia
bioRxiv · 1 Sept 2026 · Preprint
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