Integrating large microbiome cohorts with smaller metabolome data reveals robust microbiome-metabolome-disease links using a novel multi-reference framework.
- Open access
Metabolomics and Mass Spectrometry Studies
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NMFBatch reduces technical variation by effectively correcting batch effects in proteomics data, demonstrated across diverse datasets including plasma and single-cell samples.
- Open access
Hepatic and serum metabolite levels show weak correlation, with liver metabolites more strongly associated with steatosis and inflammation than serum metabolites in severe obesity.
Chronic multi-metal exposure in solar greenhouse workers is linked to significant alterations in serum amino acid profiles, with a notable negative joint effect on six amino acids.
MetaboCensoR reduces feature redundancy by up to 50% in untargeted LC-MS metabolomics, significantly enhancing data interpretability across diverse biological samples.
- Open access
Metabolic signatures of ischemic stroke and hypertensive subtype identified with diagnostic models achieving AUCs over 0.86 in validation sets.
- Open access
Exposome research in IBD highlights the importance of environmental factors, including microplastics and nanoplastics, for understanding disease risk and prevention strategies.
Multi-omics integration has revealed complex microbial functions across diverse environments, with datasets encompassing genomic, transcriptomic, proteomic, and metabolomic data.
- Open access
Integrated proteomic and metabolomic analyses reveal a distinct molecular signature of acute mountain sickness with 3,137 proteins and 4,104 metabolites differentiating affected individuals.
- Open access
Brown adipose tissue reduces hepatic oxidative stress by releasing 3-hydroxystearic acid, a cold-induced metabolite that modulates liver mitochondrial function.
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Topics moving, week to 23 Oct 2026
- Single-cell and spatial transcriptomics6
- Neuroinflammation and Neurodegeneration Mechanisms5
- Bacteriophages and microbial interactions5
- Gut microbiota and health5
- Genomics and Phylogenetic Studies4
- Cancer Genomics and Diagnostics4
- Cancer Immunotherapy and Biomarkers4
- Alzheimer's disease research and treatments3
- Inflammatory Bowel Disease3
- Influenza Virus Research Studies3