Cystic Fibrosis Research Advances

Moving in bioRxiv, Cell Reports, Cellular & molecular immunology, Journal of hepatology, medRxiv, mSystems, Nature and Nature Communications.

Moved, week to 23 Oct 2026: 0
Papers in 60 days: 12

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Pseudomonas turns protection into pathology.
Nature Microbiology · 21 Oct 2026 · Journal Article
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Respiratory ciliary abnormalities in heterotaxy beyond primary ciliary dyskinesia: functional and ultrastructural characterisation
medRxiv · 16 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.03.17.26348660
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Platelet-derived serotonin epigenetically programs macrophage alternative activation to orchestrate type 2 airway inflammation.
Cellular & molecular immunology · 1 Oct 2026 · Journal Article
Platelet-derived serotonin activates macrophage epigenetic reprogramming via TGM2, promoting type 2 airway inflammation in mice and humans.
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Endosulfan rewires GSK3β to disrupt primary cilia-dependent Hedgehog signalling
bioRxiv · 30 Sept 2026 · Preprint
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Tobramycin enhances Mycobacterium abscessus fitness through whiB7 induction.
Proceedings of the National Academy of Sciences · 22 Sept 2026 · Journal Article
Tobramycin increases Mycobacterium abscessus survival by inducing whiB7, promoting persistent infection in cystic fibrosis airway conditions.
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Mesenchymal drift in ciliopathy iPSC-derived RPE reveals a convergent pathogenic cell state.
Cell Reports · 22 Sept 2026 · Journal Article
Ciliopathy iPSC-derived RPE uniformly exhibit mesenchymal drift driven by TGF-β signaling, revealing a common pathogenic cell state across diverse genetic mutations.
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Host-pathogen pyrimidine metabolism drives cystic fibrosis lung disease.
Nature Communications · 22 Sept 2026 · Journal Article
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Within-host population structure, migration, and parallel adaptive evolution of Pseudomonas aeruginosa in cystic fibrosis lung disease.
mSystems · 22 Sept 2026 · Journal Article
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CRISPR activation of endogenous PKD1 increases polycystin-1 levels and suppresses cellular features of ADPKD
bioRxiv · 2 Sept 2026 · Preprint
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Refining risk stratification and care pathways in pediatric MASLD.
Journal of hepatology · 1 Sept 2026 · Letter
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Amygdala astrocyte primary cilium mechanisms contribute to stress behaviours.
Nature · 1 Sept 2026 · Journal Article
Amygdala astrocyte primary cilia disruption during stress impairs behavior, but restoring cilia improves stress responses and molecular markers.
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A first-in-kind MAPK13 inhibitor corrects stem cell reprogramming and muco-obstructive lung disease
bioRxiv · 28 Aug 2026 · Preprint
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https://jclub.com.au/a/10.1101/2024.08.21.608990
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