Herpesvirus Infections and Treatments

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A Tissue-Targeted Immunotherapy Protects Against Recurrent Ocular Herpes Infection and Disease, and Alleviates the Associated Cognitive, Behavioral, and Social Deficits in a 'Humanized' HLA Transgenic Mouse Model of UVB-Induced Reactivation
bioRxiv · 2 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.27.754856
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Targeting DNA-PK is a highly conserved poxvirus innate immune evasion mechanism
bioRxiv · 1 Oct 2026 · Preprint
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https://jclub.com.au/a/10.1101/2024.10.06.616852
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A case of Bundibugyo virus disease treated with monoclonal antibodies and remdesivir.
Nature Medicine · 1 Oct 2026 · Case Reports
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https://jclub.com.au/a/42742180
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Glycoprotein K8.1 shapes KSHV liver and bone marrow tropism in the marmoset infection model
bioRxiv · 28 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2024.10.31.621273
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α-Herpesviruses exploit host ssDNA gap prevention pathways for GC-rich genome replication and reactivation.
Cell Reports · 25 Sept 2026 · Journal Article
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https://jclub.com.au/a/42800029
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Axonal entry and retrograde transport define HSV-1 latency establishment and reactivation potential in neurons
bioRxiv · 25 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.24.754144
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Experimental model of VZV reactivation reveals vaccine-induced mechanisms of protection against herpes zoster
medRxiv · 25 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.22.26363709
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Screening the MMV Pathogen Box reveals the mitochondrial bc(1)-complex as a drug target in mature Toxoplasma gondii bradyzoites.
eLife · 17 Sept 2026 · Journal Article
Mitochondrial bc(1)-complex is identified as a key drug target in mature Toxoplasma gondii bradyzoites, with 25-30% of humans infected globally.
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https://jclub.com.au/a/42751871
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Antiviral activity versus host response: contrasting transcriptomic footprints of four antivirals in human cytomegalovirus-infected brain organoids
bioRxiv · 3 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.05.01.722178
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