Global Cancer Incidence and Screening

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Moved, week to 23 Oct 2026: 1
Papers in 60 days: 14

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The top cancer success stories of the past 50 years, by the numbers
Nature · 5 Oct 2026
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https://jclub.com.au/a/10.1038/d41586-026-03157-1
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Effect of Screening with Multicancer Early-Detection Test on Late-Stage Cancer Diagnosis.
New England Journal of Medicine · 8 Oct 2026 · Randomized Controlled Trial
Screening with multicancer early-detection blood tests did not significantly reduce the incidence of stage III or IV cancers after three rounds in a large randomized trial.
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https://jclub.com.au/a/42776074
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Shaping the future of early-onset colorectal cancer prevention.
Nature Reviews Cancer · 1 Oct 2026 · Review
Early-onset colorectal cancer (EOCRC) under age 50 is increasing globally, with lifestyle and early-life gut microbial exposures linked to its rise.
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https://jclub.com.au/a/42649278
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Performance and safety of a multi-cancer early detection test: the PATHFINDER 2 study.
Nature Medicine · 1 Oct 2026 · Clinical Trial
The multi-cancer early detection (MCED) test in the PATHFINDER 2 study achieved a cancer detection rate of 0.54% among participants aged 50 or older, with a CSO prediction accuracy of 91.3%.
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Performance of a multi-cancer early detection test in the randomized controlled NHS-Galleri trial.
Nature Medicine · 1 Oct 2026 · Randomized Controlled Trial
The multi-cancer early detection test in the NHS-Galleri trial detected primary cancers in 0.40% to 0.60% of participants across three screening rounds.
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https://jclub.com.au/a/42773209
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Extracting smoking history from clinical notes for lung cancer screening decision support: comparing a structured-judgment model with general-purpose large language models
medRxiv · 26 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.24.26363906
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An LLM-Based Auditing Framework for Targeted Quality Assurance in Cancer Registries
medRxiv · 26 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.22.26363595
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Effectiveness of a Community-Based Cervical Cancer Stigma Reduction Intervention on Cancer Stigma and Cervical Cancer Screening Uptake in Nepal: A Cluster-Randomized Controlled Trial
medRxiv · 25 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.24.26363856
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Developing cancer-control policies to address the cancer burden among young adults.
Nature Medicine · 24 Sept 2026 · Letter
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https://jclub.com.au/a/42786304
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Trends and differences in breast cancer mortality by race, region and age among Brazilian women, 1996-2024: a nationwide ecological study
medRxiv · 23 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.18.26363058
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Precision prevention and early detection: framework for a new clinical cancer control pathway.
The Lancet · 18 Sept 2026 · Review
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https://jclub.com.au/a/42759527
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Breast cancer: Life extending drug is now available on NHS in England.
BMJ · 17 Sept 2026 · Journal Article
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https://jclub.com.au/a/42754295
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The Association between Marital Status and Suicide Risk Among Patients with Breast Cancer A Population-Based sIPTW Competing Risk Analysis
medRxiv · 7 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.07.01.26357044
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Global breast cancer survival estimates in 2017-2021 to advance the WHO Global Breast Cancer Initiative.
Nature Medicine · 1 Sept 2026 · Journal Article
Global 5-year breast cancer survival rates from 2017-2021 ranged from 39.1% in Africa to 88.5% in the Americas, highlighting significant regional disparities.
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Interventions for Increasing Colorectal Cancer Screening Uptake: A Systematic Review and Network Meta-Analysis.
Gastroenterology · 1 Sept 2026 · Systematic Review
Patient navigation and mailed FIT outreach significantly increase colorectal cancer screening uptake, especially in populations with low baseline rates, with risk ratios of 1.58 and 1.36 respectively.
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