Hybridization occurs across nearly all eukaryotic lineages, with estimates suggesting it is more common and influential in evolution than previously thought.
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Moving in Nature and Nature Reviews Genetics.
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Hybridization occurs across nearly all eukaryotic lineages, with estimates suggesting it is more common and influential in evolution than previously thought.
Human centromeres exhibit extensive diversity with 226 haplotypes and up to 6% featuring di-kinetochore structures across populations.
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Haplotype-rich cis-regulatory variation explains a significant portion of transcriptomic diversity in maize, with 77.7% of fine-mapped eGenes showing multiple credible sets.
EZHIP evolved rapidly under positive selection in primates and exhibits dynamic expansions and losses across mammalian species, especially in placental mammals.
The genome of Xiphinema index reveals a vertebrate-like epigenetic machinery and a unique plant-derived horizontal gene transfer linked to parasitism.
Recent advances in site-specific DNA methylation and demethylation enable targeted epigenetic editing in plants, offering new avenues for crop improvement.
PlantGeneAnn achieves a new state-of-the-art F1 score of 0.856 at the exon level in plant gene annotation across 20 species, outperforming existing tools.
PanTEon reveals that machine learning-based transposable element classifiers show markedly variable performance across TE superfamilies and eukaryotic lineages.
Micronuclear ecDNA formation under replication stress reduces tumor cell fitness and is linked to improved survival in MYCN-amplified neuroblastoma patients.
Large-scale chromosomal rearrangements and repeat expansions in coleoid cephalopods are linked to species-specific chromatin loops and regulatory patterns.
Germline hypomethylation creates CpG-rich reservoirs in ape genomes, especially in dynamic regions like peri/centromeric satellites, influencing genome evolution.
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