Heart Failure Treatment and Management

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Moved, week to 23 Oct 2026: 0
Papers in 60 days: 11

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Prognostic impact of late left ventricular reverse remodeling in heart failure with reduced ejection fraction
medRxiv · 22 Oct 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.10.10.25337780
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Reinforcement Learning for Chronic Care Pathway Optimization: A Unified Framework across Three Clinical Goal Types
medRxiv · 3 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.07.03.26357209
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Empowering Singaporeans to better manage chronic heart failure: Protocol for a mixed-methods study
medRxiv · 1 Oct 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.07.09.26357623
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Short-term effects of combinations of heart failure therapies on blood pressure, kidney function and serum potassium.
Nature Medicine · 1 Oct 2026 · Journal Article
Combination heart failure therapies significantly lower systolic blood pressure by up to 9.2 mmHg in HFrEF patients and around 5 mmHg in HFmrEF/HFpEF, with manageable effects on kidney function and potassium levels.
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https://jclub.com.au/a/42675244
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New-Onset Heart Failure in Patients with Obesity using Tirzepatide or Semaglutide
medRxiv · 26 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.21.26363546
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Heart Rate and Cardiovascular Outcomes in Post-Myocardial Infarction Patients Treated by β-Blockers: A Secondary Analysis of the ABYSS Trial.
Circulation · 22 Sept 2026 · Equivalence Trial
Higher heart rates above 50 bpm in stable post-myocardial infarction patients are linked to increased adverse cardiovascular events and mortality, even in the modern reperfusion era.
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https://jclub.com.au/a/42267437
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Multimodal data-driven clustering analysis of heart failure patients identifies two distinct patterns of heart failure with preserved ejection fraction: Results from the PACIFIC-PRESERVED study.
Nature Communications · 15 Sept 2026 · Observational Study
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https://jclub.com.au/a/42875459
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Leveraging Real-World Evidence to Inform Regulatory, Clinical, and Coverage Decisions Related to Glucagon-like Peptide-1-Based Therapies: Synopsis of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop.
Annals of Internal Medicine · 1 Sept 2026 · Journal Article
Robust real-world evidence is essential to optimize GLP-1 receptor agonist use and inform policy decisions amid expanding indications and diverse populations.
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https://jclub.com.au/a/42372278
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Pulmonary Denervation for Heart Failure-Related Pulmonary Hypertension.
New England Journal of Medicine · 30 Aug 2026 · Journal Article
Pulmonary-artery denervation reduces clinical worsening by nearly 50% in patients with heart failure-related pulmonary hypertension compared to medical therapy alone.
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https://jclub.com.au/a/42670986
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Heterogeneous Treatment Effects in HFpEF: Distinguishing Drug-Specific Response from Prognostic Phenotypes Across Randomized Trials
medRxiv · 28 Aug 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.07.06.26357251
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Deprescribing in Patients With Cardiovascular Disease Experiencing Polypharmacy: A Scientific Statement From the American Heart Association.
Circulation · 25 Aug 2026 · Review
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