Unidirectional cross-feeding constrains adaptive evolution in both microbial species over 800 generations, with lower mutation fixation and increased dependence observed.
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Molecular Biology and Evolution
Oxford University Press · Genomics & Bioinformatics · ISSN 0737-4038, 1537-1719
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Unidirectional cross-feeding constrains adaptive evolution in both microbial species over 800 generations, with lower mutation fixation and increased dependence observed.
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BREATH improves phylogenetic resolution and estimates the outbreak origin more precisely by integrating transmission processes in outbreak analysis.
Genomic regions and candidate genes linked to high-altitude adaptation, including ultraviolet radiation response genes, were identified in 146 pig populations using integrated GEA methods.
Procapra species show that census size alone does not predict genetic risk, with MG having the highest genetic diversity and PG experiencing severe demographic decline despite a larger census size.
Some CNN architectures in population genetics implicitly learn summary statistics like pairwise heterozygosity, with long-range linkage disequilibrium being efficiently approximated.
Contrasting host adaptation trends and high biosynthetic potential are revealed in the Clostridia class, with species showing significant differences in genomic divergence and lifestyle specialization.
Accounting for genotype uncertainty and structured migration in low-coverage sequencing data reduces false negatives in detecting adaptive variation in populations.
DNA methylation differences between seasonal wing forms of Bicyclus anynana butterflies are mainly enriched in housekeeping genes and not associated with wing development genes.
Ancient whole genome duplication in vertebrates is linked to the functional divergence of cytochrome c, with testis-type proteins showing higher resistance to hydrogen peroxide.
Long-read sequencing revealed 5.7 million structural variants in three conifer species, with 97% in non-coding regions and 60% overlapping transposable elements.
Genome-wide genetic correlations between ER+ breast cancer risk and reproductive traits are low and not statistically significant in European populations.
Cis-regulatory elements in brown bears show dynamic activity shifts during hibernation, with many sharing homology to human enhancers but targeting different genes.
Ultra-short introns shorter than 30 bp have evolved independently at least twice within animals, with median lengths as short as 22 bp in parasitic cnidarians.
kamino provides a fast, alignment-free method that accurately recovers phylogenetic relationships across diverse prokaryotic and eukaryotic datasets.
Whole-genome analysis reveals that Octopus bimaculatus has experienced stronger positive selection than O. bimaculoides over the past million years, with more adaptive mutations fixed.
Most loci under balancing selection are likely invisible to genome scans, with detectable loci showing large, symmetrical fitness effects, especially in Drosophila-like species.
A new method using gene topologies accurately delineates sex chromosome strata and their evolutionary histories in Silene and Artemia species.
Natural selection significantly influences metabolite abundance in Saccharomyces cerevisiae, with approximately 28.58% of metabolites under potential directional selection.
Male-female expression imbalance of X-linked genes is widespread across phrynosomatid lizards, with female-biased expression observed in both ancestral and neo-X regions.
Class I fumarases are mainly found in bacteria and select eukaryotic groups, with their distribution suggesting horizontal gene transfer from bacteria to eukaryotes.
Mito-nuclear incompatibility in black soldier flies disrupts mitochondrial function and peroxisome-mediated fatty acid metabolism, involving ACOX1 and ACOX3 genes.
Herd immunity in stationary-phase Escherichia coli promotes homologous recombination, increasing gene flow by up to two orders of magnitude compared to spontaneous mutation.
Recurrent gene duplications, inversions, and tandem repeats drive the dynamic evolution of salivary proline-rich protein genes in primates, with humans showing reduced expression levels.
Deep-branching ciliates experienced massive intron loss and show a dominance of tiny 3n introns, contrasting with derived ciliates' more uniform intron distribution.
DAIseg, a new HMM-based method, jointly detects Neanderthal and Denisovan introgressed segments in modern human genomes, outperforming existing approaches in simulations and real data.
Invasive Euwallacea fornicatus populations show minimal nuclear variation but hybridization events, revealing complex invasion dynamics and hybrid origins across continents.
Asexual Aspidoscelis tesselatus lineages accumulate deleterious mutations at higher rates than their sexual ancestors, supporting Muller's ratchet predictions.
Bacterial chromosomes acquire and lose toxin-antitoxin systems rapidly, with most TAs being short-lived and often lost through deletion or pseudogenization.
A highly prevalent Mega-NUMT with up to 60 mitochondrial genomes is stably integrated into the nuclear genome of Drosophila paulistorum, found in 40% of populations.
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Topics moving, week to 23 Oct 2026
- Single-cell and spatial transcriptomics6
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