Research progress on nanomaterials in promoting phage function and application.

Nanomaterials significantly enhance phage stability, detection sensitivity, targeted delivery, and antibacterial efficacy, advancing phage therapy applications.

• Why it matters: Addressing antibiotic resistance requires effective phage-based treatments, but clinical use is limited by issues like poor stability and narrow host range, which nanomaterials may help overcome.
• What they did: The review systematically summarizes recent research on various nanomaterials—including polymer nanomaterials, liposomes, metal, and magnetic nanomaterials—focusing on their roles in improving phage function.
• The result: This synthesis offers a coherent framework for designing phage-nanomaterial strategies, providing insights to develop more effective, reliable antimicrobial therapies.