Fibroblast Growth Factor Research

Moving in bioRxiv, Blood, Cancer Research, Gut and Journal of hepatology.

Moved, week to 23 Oct 2026: 0
Papers in 60 days: 8

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A prioritized medium-throughput screen identifies fibroblast growth factors as protective for human stem cell derived insulin secreting beta cells
bioRxiv · 11 Oct 2026 · Preprint
FGF4, FGF5, FGF8F, FGF19, and FGF21 significantly enhance survival of human stem cell-derived insulin-secreting beta cells, with FGF4 and FGF5 showing the strongest effects.
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https://jclub.com.au/a/10.1101/2025.02.12.637990
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Systemic therapy of biliary tract cancer: The road to personalised strategies.
Journal of hepatology · 1 Oct 2026 · Review
Targeted therapies for intrahepatic cholangiocarcinoma with FGFR2 fusions/rearrangements show meaningful response rates and durable disease control.
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https://jclub.com.au/a/42550920
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Juvenile protein restriction compresses sexual dimorphism in mice
bioRxiv · 29 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2025.07.09.663702
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Context-specific genetic interaction mapping reveals combinatorial KRAS/FGFR dependence in pancreatic cancer
bioRxiv · 25 Sept 2026 · Preprint
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https://jclub.com.au/a/10.64898/2026.09.24.754062
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Distinct phenotypic consequences of cholangiocarcinoma-associated FGFR2 alterations depend on biliary epithelial cell state
bioRxiv · 22 Sept 2026 · Preprint
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https://jclub.com.au/a/10.1101/2024.08.30.610360
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SEPTIN7 Enhances Tumorigenesis and Therapeutic Resistance in Hepatocellular Carcinoma by Promoting FGFR4 Stabilization and Recycling.
Cancer Research · 15 Sept 2026 · Journal Article
SEPTIN7 promotes hepatocellular carcinoma progression and therapy resistance by stabilizing FGFR4 and enhancing its recycling, with knockout suppressing tumor development.
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https://jclub.com.au/a/42406998
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SDC1(+) CAFs secreting CTGF drive tumour metastasis via FGFR3 signalling in cancers.
Gut · 7 Sept 2026 · Journal Article
SDC1-positive cancer-associated fibroblasts universally promote metastasis across multiple cancers via CTGF secretion and FGFR3 activation, with 554 samples analyzed.
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https://jclub.com.au/a/41667240
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Erythroid-produced intact FGF23 is a paracrine inhibitor of erythropoiesis.
Blood · 27 Aug 2026 · Journal Article
Erythroid-produced intact FGF23 acts as a paracrine inhibitor of erythropoiesis, contributing to anemia in mice models of iron deficiency and chronic kidney disease.
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https://jclub.com.au/a/42013007
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